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Featured submissions

February 2019

January 2019 

  • Computer Aided System for Users with Visual Impairments

    Kirboyun, Sevgi; Univ Arizona, Coll Educ, Dept Disabil & Psychoeduc Studies (IEEE, 2018)
    Screen readers enable people with visual impairment (VI) to have equal access to written information both on computers and smartphones. This paper presents an overview of screen readers that allow users with VI read the text materials and describe images on the computer screen by using a special software program to synthesize as speech. We study three aspects of the screen readers in terms of their accessibility. First, we invest on developing websites, apps, and software programs by following web content accessibility guidelines to ensure accessibility. We than conduct research on compatibility of the websites, apps, and software programs with screen readers. Last, we inform about descriptions of the images by creating alternative texts.

    Gillette, Andrew; Kloefkorn, Tyler; Univ Arizona, Dept Math (AMER MATHEMATICAL SOC, 2019-03)
    We introduce the family of trimmed serendipity finite element differential form spaces, defined on cubical meshes in any number of dimensions, for any polynomial degree, and for any form order. The relation between the trimmed serendipity family and the (non-trimmed) serendipity family developed by Arnold and Awanou [Math. Comp. 83 (2014), pp. 1551-1570] is analogous to the relation between the trimmed and (non-trimmed) polynomial finite element differential form families on simplicial meshes from finite element exterior calculus. We provide degrees of freedom in the general setting and prove that they are unisolvent for the trimmed serendipity spaces. The sequence of trimmed serendipity spaces with a fixed polynomial order r provides an explicit example of a system described by Christiansen and Gillette [ESAIM: M2AN 50 (2016), pp. 883-850], namely, a minimal compatible finite element system on squares or cubes containing order r - 1 polynomial differential forms.
  • Cardiac autonomic activity during simulated shift work

    SKORNYAKOV, Elena; GADDAMEEDHI, Shobhan; PAECH, Gemma M.; SPARROW, Amy R.; SATTERFIELD, Brieann C.; SHATTUCK, Nita L.; LAYTON, Matthew E.; KARATSOREOS, Ilia; VAN DONGEN, Hans P. A.; Univ Arizona, Social Cognit & Affect Neurosci Lab, Dept Psychiat, Coll Med (ELSEVIER GMBH, 2019-02)
    Shift work leads to adverse health outcomes including increased risk of cardiovascular disease. Heart rate (HR) and heart rate variability (HRV) arc measures of cardiac autonomic activity and markers of cardiovascular disease and mortality. To investigate the effects of shift work on cardiac autonomic activity, we assessed the influence of simulated night work on HR and HRV, and dissociated the direct effects of circadian misalignment from those of sleep displacement and altered physical activity patterns. A total of 29 subjects each participated in one of two in-laboratory, simulated shift work studies. In both studies, EKG was continuously monitored via Holter monitors to measure HR and the high frequency (HF) component of HRV (HF-HRV). We found endogenous circadian rhythmicity in HR and HF-HRV. Sleep and waking physical activity, both displaced during simulated night work, had more substantial, and opposite, effects on HR and HF-HRV. Our findings show systematic but complex, interacting effects of time of day, sleep/wake state, and physical activity on cardiac autonomic activity. These effects need to be taken into account when evaluating HR and HRV in shift work settings and when interpreting these measures of cardiac autonomic activity as markers of cardiovascular disease.
  • Soil exchange rates of COS and COO differ with the diversity of microbial communities and their carbonic anhydrase enzymes.

    Meredith, Laura K; Ogée, Jérôme; Boye, Kristin; Singer, Esther; Wingate, Lisa; von Sperber, Christian; Sengupta, Aditi; Whelan, Mary; Pang, Erin; Keiluweit, Marco; Brüggemann, Nicolas; Berry, Joe A; Welander, Paula V; Univ Arizona, Sch Nat Resources & Environm; Univ Arizona, Biosphere 2 (NATURE PUBLISHING GROUP, 2019-02-01)
    Differentiating the contributions of photosynthesis and respiration to the global carbon cycle is critical for improving predictive climate models. Carbonic anhydrase (CA) activity in leaves is responsible for the largest biosphere-atmosphere trace gas fluxes of carbonyl sulfide (COS) and the oxygen-18 isotopologue of carbon dioxide (CO
  • Lymphangiogenesis, lymphatic systemomics, and cancer: context, advances and unanswered questions.

    Dellinger, Michael T; Witte, Marlys H; Univ Arizona, Dept Surg, Coll Med (SPRINGER, 2018-08-01)
    Ever since it was discovered that endothelial cells line lymphatic vessels, investigators have been working on unraveling the mechanisms that control the growth of this distinctive endothelium and its role in normal physiology and human disease. Recent technological advances have ushered in a new era of "omics" research on the lymphatic system. Research on the genome, transcriptome, proteome, and metabolome of lymphatics has increased our understanding of the biology of the lymphatic vasculature. Here, we introduce the context-lymphatic "systemomics," then briefly review some of the latest advances in research on tumor-associated lymphatic vessels highlighting several "omic" studies that have shed light on mechanisms controlling the growth and function of tumor-associated lymphatic vessels. We conclude by returning, with unanswered questions, to the larger context of cancer and the lymphatic system as a vasculature, circulation, route of entry and transport, and control center of the immune network.

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