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Featured submissions
March 2021
- Do you have research data and code to share? Visit ReDATA, The University of Arizona Research Data Repository to learn how to make your data and code available in compliance with funder mandates
- Rangeland Ecology & Management, Volumes 67-68 (2014-2015) are now publicly available in the repository.
- Tree-Ring Research, Volume 71 (2015) is now publicly available in the repository.
February 2021
- Meteoritics & Planetary Science, Volumes 37-44 (2002-2009) are now publicly available in the repository.
- Radiocarbon, Volumes 1-54 (1959-2012) are now publicly available in the repository.
- Theses from Spring/Summer 2020 Honors College graduates are now publicly available in the repository.
January 2021
- Rangeland Ecology & Management/Journal of Range Management, Volumes 1-66 (1948-2013) are now publicly available in the repository.
- More than 8,400 journal articles from University of Arizona faculty, staff and researchers have been made available since the implementation of the UA Open Access Policy (April 2016). You can find these articles in the UA Faculty Publications collection - thank you to all our article authors and contributors!
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Recently Added
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QUALITATIVE INTERVIEWS WITH PARENTS ABOUT THEIR EXPERIENCE WITH THE ‘INTENSE PHYSIOTHERAPIES TO IMPROVE FUNCTION IN CHILDREN WITH CEREBRAL PALSY” CLINICAL TRIAL AT TUCSON MEDICAL CENTERThis research is a sub-study of the original ‘Intense Physiotherapies to Improve Function in Young Children with Cerebral Palsy’ study conducted by my advisors Dr. Burris Duncan and Dr. Heidi Pottinger. The sub-study was created to obtain qualitative data from the parents of children who participated in their study at Tucson Medical Center (TMC). The processes for this work included obtaining human subjects-related training to be able to interview the families, recruitment of subjects by Dr. Pottinger, preparation for interviewing parents, conducting live interviews, and analyzing qualitative data with key findings/themes identified. These findings will help to identify areas for improvement for future clinical trials/research with TMC families.
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Orthotopic Heart Transplant Recipient with Enteric-coated Mycophenolate Sodium (Myfortic) Induced ColitisObjective: Rare disease Background: Mycophenolic acid is an immunosuppressive drug commonly used in solid organ transplantation to prevent acute and chronic allograft rejection. There are 2 common preparations of mycophenolic acid including mycophenolate mofetil (Cellcept), and enteric-coated mycophenolate sodium (Myfortic) which was developed to reduce the high rate of gastrointestinal side effects seen with Cellcept. Cases of mycophenolate mofetil induced colitis have been described in solid organ transplant patients and rarely in heart transplant patients, but enteric-coated mycophenolate sodium induced colitis is very rare and has not been reported in heart transplant patients. Case Report: A 66-year old male with an orthotopic heart transplant was admitted with diarrhea. The patient was on an immunosuppression regimen including mycophenolate mofetil for 10 weeks post-transplantation until complaining of soft stools and bloating. At this time, he was switched to enteric-coated mycophenolate sodium. At week 11 post-transplantation, the patient was admitted to the hospital with worsening diarrhea. Extensive workup was unrevealing. Colonoscopy with biopsy showed features of mycophenolic acid induced colitis. Enteric coated mycophenolate sodium was discontinued, and the patient's diarrhea markedly improved over the next 48 hours. The patient had no signs of colitis or solid organ rejection at 7-month follow up appointment. Conclusions: Although a diagnosis of exclusion, enteric-coated mycophenolate sodium induced colitis should be considered in the differential of an orthotopic heart transplant patient with diarrhea as discontinuing the medication can improve symptoms and avoid costly workups, however, patients should be monitored closely for signs of rebound rejection.
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Distribution, status and conservation needs of the white-sided jackrabbit, Lepus callotis (Lagomorpha)Although an important game animal and a species of wide distribution, little is known about the natural history of the white-sided jackrabbit (Lepus callotis), its ecological requirements, and limiting factors. The information available suggests that this species may have undergone a reduction in both population numbers and distribution, and may be endangered due to habitat changes. The information presented herein should facilitate proposals for future research, and conservation and management actions.
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Reinstatement of the Tamaulipas white-sided jackrabbit, Lepus altamirae, based on DNA sequence dataIn 1904, the Tamaulipas jackrabbit (Lepus altamirae) was described as a subspecies of Lepus merriami. In 1909, E. W. Nelson assigned L. altamirae to the white-sided group of jackrabbits, and in 1951, E. R. Hall reclassified it as a subspecies of black-tailed jackrabbits (Lepus californicus altamirae). Our comparison of the original 5 specimens of the Tamaulipas jackrabbit in the U.S. National Museum suggested this taxon had a close relationship to the white-sided jackrabbit, Lepus callotis. To validate Nelson's placement of the Tamaulipas jackrabbit within the white-sided group, we conducted phylogenetic analyses using the mitochondrial cytochrome b gene (MT-CYB). Our analyses of 2 specimens collected in 1898, suggest that L. altamirae is most closely related to Lepus flavigularis, a member of the white-sided group. Therefore, the Tamaulipas jackrabbit warrants taxonomic restoration as a species within the white-sided group of jackrabbits, which also includes L. callotis, L. flavigularis, and Lepus alleni.
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The Extra Mile: Special Consideration of Atrial Fibrillation in Older Adults with Endurance Athletic HistoryObjective: Challenging differential diagnosis Background: Aerobic exercise is uniformly accepted as one of the most important modifiable factors to improve cardiovascular health, but endurance athletic training poses a significant risk factor for development of atrial fibrillation (AFib) in middle-aged and older adults. Ubiquitous risk assessment tools (CHADS2 and CHA2DS2-VASc) and US Preventive Services Task Force guidelines do not presently account for this association. A case is presented which illustrates a dire outcome of undiagnosed AFib in an elderly male patient who had run many marathons. Case Report: An 80-year-old male with well-controlled hypertension and hypercholesterolemia and a history significant for running many marathons throughout his life was brought in via ambulance after being found down with head trauma by his wife at home. A short run of AFib was recorded on telemetry and electrocardiogram (ECG) and a review of previous ECGs revealed evidence of interatrial block (Bayes Syndrome), though the patient had no history of AFib or anticoagulation. This coupled with imaging indicated thromboembolic stroke to the left middle cerebral artery leading to right-sided hemiplegia and a subsequent fall to the right, causing right-sided head trauma and intracranial hemorrhage. His clinical course did not improve, and on his fifth day of admission he was transferred to comfort care, extubated, and succumbed to his injuries. Conclusions: This case and the accompanying summary of evidence strongly encourage further investigation and a higher index of suspicion for AFib in asymptomatic older adults with a history of endurance athletic training.
