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Repository News

  • Geologic Map of the Somerton 7 1/2' Quadrangle, Yuma County, Arizona

    Youberg, A.; Arizona Geological Survey (Arizona Geological Survey (Tucson, AZ), 2011-11)
  • Geologic Map of the Peppersauce Wash 7½' Quadrangle and Part of the Kielberg Canyon 7 ½’ Quadrangle, Pinal and Pima Counties, Arizona v. 1.0

    Pearthree, P.A.; Cook, J.P.; Skotnicki, S.J.; Spencer, J.E.; Arizona Geological Survey (Arizona Geological Survey (Tucson, AZ), 2009-01)
  • Geologic Map of the Davis Dam SE 7.5' Quadrangle, Mohave County, Arizona, and Clark County, Nevada

    Pearthree, P.A.; House, K.P.; Arizona Geological Survey; U.S. Geological Survey (Arizona Geological Survey (Tucson, AZ), 2005-01)
  • OCEANUS: A high science return Uranus orbiter with a low-cost instrument suite

    Elder, C.M.; Bramson, A.M.; Blum, L.W.; Chilton, H.T.; Chopra, A.; Chu, C.; Das, A.; Davis, A.B.; Delgado, A.; Fulton, J.; Jozwiak, L.M.; Khayat, A.; Landis, M.E.; Molaro, J.L.; Slipski, M.; Valencia, S.; Watkins, J.; Young, C.L.; Budney, C.J.; Mitchell, K.L.; Univ Arizona, Lunar & Planetary Lab (PERGAMON-ELSEVIER SCIENCE LTD, 2018-07)
    Ice-giant-sized planets are the most common type of observed exoplanet, yet the two ice giants in our own solar system (Uranus and Neptune) are the least explored class of planet, having only been observed through ground based observations and a single flyby each by Voyager 2 approximately 30 years ago. These single flybys were unable to characterize the spatial and temporal variability in ice giant magnetospheres, some of the most odd and intriguing magnetospheres in the solar system. They also offered only limited constraints on the internal structure of ice giants; understanding the internal structure of a planet is important for understanding its formation and evolution. The most recent planetary science Decadal Survey by the U.S. National Academy of Sciences, "Vision and Voyages for Planetary Science in the Decade 2013-2022," identified the ice giant Uranus as the third highest priority for a Flagship mission in the decade 2013-2022. However, in the event that NASA or another space agency is unable to fly a Flagship-class mission to an ice giant in the next decade, this paper presents a mission concept for a focused, lower cost Uranus orbiter called OCEANUS (Origins and Composition of the Exoplanet Analog Uranus System). OCEANUS would increase our understanding of the interior structure of Uranus, its magnetosphere, and how its magnetic field is generated. These goals could be achieved with just a magnetometer and the spacecraft's radio system. This study shows that several of the objectives outlined by the Decadal Survey, including one of the two identified as highest priority, are within reach for a New-Frontiers-class mission.
  • HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?

    Amato, Jussara; Madanayake, Thushara W.; Iaccarino, Nunzia; Novellino, Ettore; Randazzo, Antonio; Hurley, Laurence H.; Pagano, Bruno; Univ Arizona, Coll Pharm (ROYAL SOC CHEMISTRY, 2018-09-04)
    This communication reports on a possible distinct role of HMGB1 protein. Biophysical studies revealed that HMGB1 binds and stabilizes the G-quadruplex of the KRAS promoter element that is responsible for most of the transcriptional activity. Biological data showed that inhibition of HMGB1 increases KRAS expression. These results suggest that HMGB1 could play a role in the gene transcriptional regulation via the functional recognition of the G-quadruplex.

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