• Cardiac Electrophysiological Mapping And Ventricular Tachycardia In A Model Of Chronic Heart Failure

      Juneman, Elizabeth B.; Chinyere, Ikeotunye Royal (The University of Arizona., 2019)
      In the United States, one in three deaths are attributed to cardiovascular disease (CVD) (1). Within CVD, sudden cardiac death (SCD) is an increasingly common cause of mortality, by way of ventricular tachycardia (VT) and ventricular fibrillation. A positive correlation has been found between the presence of ischemic heart failure and the likelihood of inducible VT (2-5) as well as the presence of coronary artery disease and the likelihood of experiencing SCD (6). We have developed custom electrophysiology (EP) software (7) to perform examinations to distinguish between the sub-types of ischemic myocardium in rats. Furthermore, I am able to display EP data in two dimensional colormap arrays to provide a spatially-oriented image of the myocardium. Our software is also able to induce VT, in a consistent, minimally invasive manner. Now that I have established a consistent difference in mapping and arrhythmia (8) between healthy myocardium and damaged myocardium in our model of ischemic heart failure, I have the opportunity to investigate the mechanisms by which adverse cardiac remodeling leads to an increased risk of SCD, investigate therapies, as well as an opportunity to investigate other animal models of ischemic or non-ischemic cardiomyopathies for model phenotype validation and subsequent treatment effectiveness.
    • A Comparison Of The Representation Of Women In The Northern Renaissance And Modern Day: The Occult, Female Sexuality, And The Media

      Barr, Sandra; Soehl, Morgan Marie (The University of Arizona., 2019)
      In this essay I will compare depictions of women in Northern Renaissance prints and the modern media in order to reveal the roots of stereotypical representations of women. Women who go against the status quo are represented as witches so as to prey on societal fears of female sexuality and dominance. Printmaking and the modern media both represent women with a binary understanding of femininity. How these stereotypes of women are represented in the media today have roots in Northern Renaissance prints that were heavily influenced by the Malleus Maleficarum, the first treatise on witches and the occult. This treatise utilized gendered stereotypes to describe witches, thus generating a fear of the occult that manifests as a fear of female power, particularly as it pertains to sexuality. Part one focuses on the Malleus Maleficarum as it was applied to various works of art during the 15th and 16th centuries. Part two will prove that the iconographic references utilized during the Northern Renaissance have continued on as unconscious bias within society, manifesting in the way women are represented in the media. Understanding these roots is an important step towards understanding why women have historically been relegated to a second-class status.
    • Coca Policies In Post-2005 Bolivia: The Effect On Cocalero Livelihoods In The Chapare

      Brewer-Osorio, Susan; Sharp, Bryn Deana (The University of Arizona., 2019)
      After Evo Morales was elected as Bolivia’s President in 2005, the cultivation of the coca leaf, an important economic and cultural resource for the country, became legalized in the Chapare. In this region, Morales and his administration have enacted several policies that focus on improving the livelihoods of coca-growing families (cocaleros) through cooperative reduction of coca production and the diversification of their income base. The Bolivian government claims that these policy changes have resulted in substantial improvements in the well-being of these households. This study examines the changes in wealth, (un)employment, and food security levels of cocalero households to conclude that while there has been an improvement in their livelihoods, there has not been enough change to allow for socioeconomic mobility.
    • “WHY Stay?”

      Byrne, Kevin; Esposito, Victoria (The University of Arizona., 2019)
      “Why Stay” is a play about an abusive relationship from the end to the beginning. People often ask women or men who have been in abusive relationships, “Why stay?” By showing a relationship in reverse chronological order, the intent of the piece was to delve into that question and show a new perspective. This piece was created by interviewing women who are currently or have been in domestically abusive relationships. By using their answers, the main two characters were then crafted. The piece culminated in a staged reading and was attending by faculty and students from the school of theatre, film and television. This piece is important because Tucson is a community with Emerge, a domestic abuse shelter, and yet people are not comfortable discussing their situations. They often feel ashamed of their past, so this play is a chance to change that perception.
    • The Eye Of The Scholar Of Religion: Data Analysis Report For The Department Of Religious Studies, College Of Humanities And Reflective Essay Of A Humanist Scholar Upon The Meaningful Nature Of An Education In Religious Studies

      Dachille, Rae; Forer, Chelsea Elizabeth (The University of Arizona., 2019)
      Throughout my time as a student of Religious Studies at the University of Arizona (UofA) I have come to reflect heavily on the questions “Why pursue an education in Religious Studies?” and “How is this education valuable, personally and professionally?” I developed a senior thesis project that addresses both of these questions. First, I asked my peers, fellow Religious Studies majors at the UofA, to participate in a short writing exercise that aims to engage the skills and knowledge they have gained while studying in the program. Additionally, I asked my peers to reflect upon the meaningful nature of their Religious Studies education. This report is two-fold: Part I is a summary report of my data and analysis that compares the skills displayed by current students with the learning objectives stated by the department, with the intention of providing a tangible benefit to the Department of Religious Studies and College of Humanities at the UofA. The first part of my project will be a reflective, student-based tool for the department as well as provide advertisement material for the benefits of studying in this UofA program. Part II is a personal self-reflective essay addressing my original broader research questions by considering my peers’ responses.
    • The Role Of Religion, Politics And Gender In The Visitation By The Master Of The Retablo Of The Catholic Kings

      Cuneo, Pia; O'Bert, Andrea Elena (The University of Arizona., 2019)
      The Visitation and the other seven panels in the altarpiece by the Master of the Catholic Kings are still a mystery in many ways. However, analyzing them in their political, religious and gender contexts suggests that they serve as a powerful example of political propaganda produced in favor of the Catholic monarchs. The altarpiece allows for the veneration of the saints and in the Master’s altarpiece in particular, the key saint being depicted is the Virgin Mary. It is currently believed that the Master’s altarpiece was commissioned by Queen Isabella and King Ferdinand. Their daughter, Juana of Castile, was perceived by the public as being mentally unwell and thus not fit for leadership. In an effort to improve her image before she married Philip of Hapsburg and assumed the throne, they had this altarpiece created with Mary made in the image of Juana. Throughout the scenes of Mary’s life that are depicted, she embodies many characteristics of the ideal woman: pious, maternal and obedient. In supporting that Juana embodies these traits, the King and Queen hope to counter the public’s concern about Juana’s mental illness and to provide an alternate image of her as the perfect queen to lead Spain.
    • A Creative Investigation Into Epic Poetry: Solead

      Christenson, David M.; Walker, Katherine Lauren (The University of Arizona., 2019)
      In the manner of an epyllion, this fictional poetic piece explores how a modern epic might be constructed. Using a science fiction setting, two sides of a growing conflict in Earth’s solar system are followed on their respective journeys and in their inevitable convergence as each group fights for the truths or lies they have come to believe. It also serves as an investigation into the composition process of an epic in an effort to better understand the creative choices of classical works of this genre.
    • Family Perceptions: Measuring Beliefs About Whether Gender Roles Are Transmitted From Parents To Children

      Croft, Alyssa; Coles, Mathew Ryan (The University of Arizona., 2019)
      Prior research has examined perceptions of adults who violate gender stereotypes and shown on numerous occasions that these adults are at risk for receiving social and economic repercussions in the form of perceptual evaluations. However, research has yet to address whether the negative judgements of and backlash against gender nonconforming adults will be transferred onto perceptions of their children. The current study investigates how adults perceive children belonging to non-traditional (i.e., gender non-stereotypical parental roles) and traditional households by showing adults illustrations of these ostensible children within the family context. Results show that parents belonging to non-traditional families were generally perceived in accordance with backlash theory. The non-traditional mother received higher rating of perceived success, but lower rating of perceived morality in comparison to their non-violating other. While the non-traditional father was perceived as more likable but less successful then the non-traditional mother and received lower rating of success in comparison to their non-violating other. These findings did not extend to children in the way that was originally hypothesized, and instead non-traditional children received ratings similarly to children with traditional parents but received a boost in perceived success and likelihood to pursue counter stereotypical occupations.
    • Business Innovation & Entrepreneurship: Cross-Border Opportunities In Mexico-Sonora And Athena Virtual Reality

      Yngve, Rick; Richards, Tristan Jeannette (The University of Arizona., 2019)
      As a student in the McGuire Center for Entrepreneurship program, I have developed a multitude of skills associated with business innovation and entrepreneurship. My four teammates and I have spent the last year creating a scalable new venture, Athena Virtual Reality (VR). Athena VR enables universities to customize an engaging technology to market their school to prospective students. Users are able to view college campuses, curriculum and career opportunities to improve four-year student graduation rates. Following the collection of validation research, our team developed a business plan that outlines Athena VR’s objectives and strategies to achieve the company’s overall goals. Our team also participated in several trade shows, including the New Venture Competition in which we prepared a 1-minute, 3-minute and 5-minute pitch for investors. The Honors course in this program primarily focused on cross-border business between the U.S. and Mexico-Sonora. By conducting our own research and listening to several guest speakers, we were able to expand our knowledge about Mexico’s economy, culture and relationship with the U.S. I traveled to Mexico-Sonora with my classmates to experience the region’s opportunities in business development and analyze how Athena VR can learn from and/or utilize these opportunities in its strategies.
    • Hyperoperation: Introduction To The Theory And Potential Solutions

      Pickrell, Douglas; Dalthorp, Mark (The University of Arizona., 2019)
      We investigate the sequence of hyperoperations, which begins with addition, multiplication, andexponentiation. The nth hyperoperation is defined by iterating the previous operation. We address the problem of extending hyperoperations to non-integer values. We show existence of an analytic solution, and present several approaches to construction.
    • CubeSat Camera Space Ruggedization

      Redford, Gary; Mitchell, Adriana Macieira (The University of Arizona., 2019)
      Professor Vishnu Reddy, from the Lunar and Planetary Laboratory, sponsored a University of Arizona senior design team to “space-qualify” (design, build, and test) a camera system to be integrated into a miniature satellite (CubeSat). This NASA-funded CubeSat mission, named CatSat, will be used as a technology demonstration for a high bandwidth deep space communication system which will be able to achieve HD video transmission from Low-Earth Orbit (LEO) through a novel inflatable antenna. The camera system, named CatCam, images the deployment of the inflatable antenna and captures video of Earth. The data that CatCam captures streams through the inflatable antenna as the demonstration of HD video transmission. We considered system architecture, camera controls, and integration with the entire CubeSat, and were successfully able to provide our sponsor with a working prototype.
    • Imaging Polarimeter Software Model

      Redford, Gary; Mohr, Erica (The University of Arizona., 2019)
      The polarization effects of optical systems are often hard to characterize with industry standard equipment. Polaris-M is a polarization ray tracing software that calculates the polarization effects of any optical system. This project demonstrated the efficacy of Polaris-M by modeling some commercial optics and verifying the results through measurements with the RGB950 polarimeter. The RGB950 is a custom-made Axometrics polarimeter that operates in the visible range and at 947 nm. The angular dependence of the polarimeter was also modeled by analysing data taken of air samples. Furthermore, a novel division of amplitude polarimeter was built from stock visible spectrum optics and its polarimetric performance was calculated with both a Polaris-M model and RGB950 measurements. The software models of the different optical elements tested by the polarimeter are complete and corresponding Mueller matrices were compared to measured Mueller matrix data. This includes models for a non-polarizing cube beamsplitter, a solid corner cube and the DoAP. The resulting software characterizing the polarimeter shall be presented to the Polarization Lab at the University of Arizona for use in predicting polarization measurements and verifying instrument performance.
    • Visual Natural Language Processing Of Medical Images For Enhanced Value

      Redford, Gary; Alcantara, Diego Kantack (The University of Arizona., 2019)
    • Wide Area Drone Situational Awareness

      Redford, Gary; Donovan, Nathan (The University of Arizona., 2019)
      The paper Wide Area Drone Situational Awareness gives an in-depth walk through the Eyes in the Dark (EitD) drone detection system. The EitD system was designed to scan a portion of the sky for the presence of a drone. If the system detects a drone, EitD then uses its ability to alert a user to the detected object. Raytheon created the project to help secure small private airports from the ever-growing threat of small hobby drones. The EitD prototype satisfies all functional requirements except for the 400m distance requirement, which was not obtainable within the budget for the project. Both physical testing and theoretical analysis is presented to demonstrate the systems capabilities and areas of future work.
    • Bruise Age Measurement Sensor Project 18078

      Redford, Gary; Shumaker, Alexa Marie (The University of Arizona., 2019)
      Bruise Age Measurement Sensor Senior Design project was to build a portable device from scratch to be able to measure the age of a bruise for non-verbal child abuse victim, specifical under the age of three. Due to limited research on bruise metabolism, the aspect of aging a bruise is ongoing and the device will help aid in future bruise research. Ideally the device, with more human subject research though Institutional Review Board (IRB) approval, will help to measure how a bruise will change over time to be able to approximate the bruise. The device was designed via solidwork and 3D printed to be handheld, portable, and battery powered. As well the device uses Arduino and Teensy Microcontrollers, a micro-spectrometer, eight LEDs, and a micro-SD card. The device takes measurements within seconds, turns on all LED’s, the spectrometer gets the spectroscopic readings, and transfer the recorded intensities to be stored on a removable SD card. Once bruise metabolism research is completed, and the approximation of a bruise is able to be defined this device can eventually be used the field by physicians, social workers, and law enforcement officers.
    • Effects Of Mindfulness-Based Cognitive Therapy On Autobiographical Memory In Formerly Depressed Women

      Andrews-Hanna, Jessica; Mamaril, Erin Marie (The University of Arizona., 2019)
      Autobiographical memory is overgeneral in both current and remitted major depressive disorder. This cognitive pattern has been hypothesized to be one of the contributing vulnerabilities that makes relapse of depression a significant public health issue. Mindfulness-based cognitive therapy (MBCT) targets depressive relapse, and prior literature suggests that MBCT improves autobiographical memory. This thesis investigates the effect of an online version of MBCT on autobiographical memory in formerly depressed women using a quantitative measure of memory specificity. Formerly depressed women and healthy controls completed an Autobiographical Memory Test at two sessions, between which the formerly depressed participants underwent an 8-week online MBCT intervention. Healthy controls demonstrated greater memory specificity than formerly depressed women at both sessions, but trend for a group by time interaction was found such that formerly depressed women experienced a greater increase in memory specificity between sessions. Furthermore, an association was found for formerly depressed women between reductions in depressive symptoms and increases in memory specificity, suggesting that a positive response to MBCT is related to improvements in autobiographical memory. This study implicates effects on memory specificity as a mechanism of change by which MBCT prevents depressive relapse, making this a potential target to refine interventions.
    • Karyometry Identifies A Deviant Phenotype In The Fallopian Tube Epithelium Of Postpartum Subjects And Subject At High Risk Of Ovarian Cancer

      Alberts, David S.; Alturi, Sri Sai Swetha (The University of Arizona., 2019)
      With the highest mortality rate of all gynecologic cancers, ovarian cancer is a deadly reproductive malignancy among women. Previous studies have identified the fallopian tube epithelium to be the site of origin for high grade serous ovarian carcinoma. Survival is high when the cancer is discovered while it is still localized to the site of origin, but it is rarely detected that early due to the late manifestation of symptoms and ineffectiveness of current screening methods. Karyometry is a quantitative histopathology technique that detects chromatin abnormalities at the nuclear level using imaging analysis. This study investigates whether karyometry can detect nuclear abnormalities of fallopian tube epithelium in women carrying the BRCA1 or BRCA2 mutation versus the fallopian tube epithelium of women who are at normal risk of developing ovarian cancer. Fallopian tube tissue from 11 women who were at normal risk, 13 women who carried the BRCA1 or BRCA2 mutation, and 13 postpartum women was analyzed using karyometry. There was a distinct deviation in mean nuclear signatures between the normal and high risk groups and between the normal and postpartum groups. In this preliminary analysis, karyometry detected nuclear abnormalities in the fallopian tube epithelium of high risk women.
    • Design Of Hyperspectral Imaging Smartphone Lens Attachment And Application

      Redford, Gary; Thorne, Travis David (The University of Arizona., 2019)
      Hyperspectral Imaging is an emerging imaging technique that captures an entire spectrum of light for every pixel in the detector array of the imaging system. Hyperspectral Imaging is now increasingly used in applications such as food safety, drug detection, cancer screening, and environmental analysis. Previously designed systems have historically been very large, non-portable, and expensive. Hellman Optics has filed a patent for a novel approach to enable the capture of hyperspectral image data by creating a simple smartphone lens attachment and application, allowing the benefits of hyperspectral data to enrich the lives of everyday consumers. An in-depth report of the design and testing of this system is contained in this thesis, culminating in the conclusion that the designed system meets specifications to enable the future capture of hyperspectral imaging data.
    • Common Sense And Capitalism: An Observation Of The Production Of Information Technology In The Context Of A Capitalist Economy

      Thompson, Richard; Smith, Hannah Kathleen (The University of Arizona., 2019)
      The purpose of this project is to identify trends in production in a capitalist economy, but it is also to make the viewer aware or their own capabilities of observation. By collecting data from public online sources and performing analysis with the programming language Python, I have identified several trends. I then speculated the potential causes of these trends, reflecting on research articles regarding production systems and incentives in a capitalist economy. This analysis is important because it takes a widespread idea (the benefit of capitalism in production) and applies ‘good sense’ – an idea proposed by philosopher Antonio Gramsci – to an idea that is typically promoted as common sense. The analysis itself allows for educated critiques on the quality of the capitalist system, and the idea of ‘goof sense’ promotes critiques on all widely-held yet seldom-questioned beliefs in our society.
    • System On A Chip Video Encoding System

      Redford, Gary; Muir, Ezra James (The University of Arizona., 2019)
      The goal of the project was to evaluate the Zynq Ultrascale+ MPSoC device for its potential use in digital signal processing and digital wireless communications applications. The evaluation was divided into three distinct phases. The first phase being a conversion of existing fixed-point complex math C library functions to operate using ARM NEON intrinsic functions. The second phase was the creation and execution of a program which performs complex, discrete-time cross-correlation to be run as a timed benchmark on the device. Finally, the third phase was to design a demonstration which utilizes the video encoding capabilities, as well as its ability to interface with a software-defined radio device, to implement a signal capture camera. The project resulted in success in all three phases. The functions, which were successfully converted, were utilized in the cross-correlation benchmark. The timed benchmark resulted in cross-correlating one-million 320 complex element random input arrays against a 40 complex element reference array in an average of 2624.6 seconds. The result of the demonstration is a system which simultaneously runs a GNU Radio flowgraph to operate a BPSK receiver on the software-defined radio while also encoding and decoding video being captured by a camera to be displayed.