• The 150-Hour Rule: How Policy Decisions Affect the Supply of Public Accountants

      McLeod, Martha Lamb (The University of Arizona., 2011-05)
    • 17β Estradiol Decreases Vasodilation at 31°C in Ovariectomized Rats

      Brown, Jessica Nicole (The University of Arizona., 2010-05)
      The purpose of this Honor's Thesis is to investigate rat heat dissipation in correlation with estradiol (commonly referred to as estrogen) at different environmental (ambient) temperatures. The relevance of this study is investigative of post-menopausal hot flushes as a thermoregulatory dysfunction.
    • The 1979 Iranian revolution: the revolutionary revolution

      Brandis, Dov Asher (The University of Arizona., 2009-05)
    • 2-HYDROXYETHYL HYDRAZINE AND HYDRAZINE HYDRATE PLANT DESIGN

      Hsu, Ivann Hong; Emerson, Joanna; Wong, Andrew; Zinsli, Phillip (The University of Arizona., 2009-05)
    • 2-HYDROXYETHYLHYDRAZINE (HEH) PLANT DESIGN

      Emerson, Joanna Louise (The University of Arizona., 2009-05)
    • 2-HYDROXYETHYLHYDRAZINE (HEH) PLANT DESIGN

      Zinsli, Phillip Alexander (The University of Arizona., 2009-05)
    • The 2012 Presidential Election Gender Gap

      Caicedo, Andrea (The University of Arizona., 2015)
      The gender gap in presidential elections has been an important part of American politics for the past decades. This phenomenon in politics refers to the differences of men and women in party identification and voting behavior. This paper explains the origins of the gender gap dating back to the 1980s. It explains the patterns and analyzes the most significant issues in each presidential election. Finally, it analyzes the gender gap in the 2012 presidential election. It focuses on the issues that had the biggest difference and it explains why some issues are more susceptible to having a greater gender gap.
    • 2015-2016 UA|ASME HUMAN POWERED VEHICLE PROJECT: MAGNUM

      LEISTER, DAVID EDWARD (The University of Arizona., 2016)
      The American Society of Mechanical Engineers (ASME) hosts the annual Human Powered Vehicle Challenge (HPVC), in which student design teams from universities and colleges around the world design, build, and compete human powered vehicles. A human powered vehicle is just any vehicle whose motive power comes from the exertion of its driver(s). The University of Arizona’s (UA) entry in the 2016 HPVC West, Magnum, succeeds Blue Steel (2013), Le Tigre (2014), and Ferrari (2015). It is the most ambitious project undertaken by the UA human powered vehicle team, featuring a carbon fiber/aluminum hybrid frame and full fairing, and a custom built steering system. An onboard electronics suite includes turn signals, a traffic horn, and a novel Roll Alert System, an Android app developed by the team to alert everyone in the event of a vehicle rollover or crash. Both the mechanical and electronic systems were designed and built from the ground up by this year’s team. Magnum is also the best-performing UA human powered vehicle in recent history, earning Top 10 ranks in the 2016 HPVC West’s Design and Innovation categories, and 13th overall.
    • 2016 CHICAGO QUANTITATIVE ALLIANCE INVESTMENT CHALLENGE: U OF A CQA TEAM - INVESTMENT STRATEGY

      CARLSON, JONATHAN ANDERS (The University of Arizona., 2016)
      For my finance, honors thesis I participated in the 4th annual CQA Investment Challenge. The goal of the challenge is to successfully manage an equity long-short, market neutral portfolio (hedge fund). I worked on a team with three other guys from the Applied Portfolio Management class to invest and manage $20,000,000 of hypothetical money. Our investment horizon ran from October 30, 2015 – April 1, 2016. The stock universe we had access to was the Russell 1000, which mainly consists of the highest-ranking large cap stocks in the US equity market. Thirty-one teams from different universities were judged at the end of the competition on absolute return rank, adjusted return rank (the Sharpe ratio) and evaluation of the team video, which discussed investment strategy. The University of Arizona team achieved an absolute return of 6.47%, Sharpe ratio of 0.36 and abnormal return (alpha) of 20.05%. We finished with a ranking of 7th place out of 31 participating schools.
    • 2017 Chicago Quantitative Alliance Investment Challenge: University of Arizona CQA Investment Strategy

      To, Kham Hong; Hascalovici, Hilla; Bateman, Spencer; Recchion, Edward; Recchion, Charles (The University of Arizona., 2017)
      The CQA challenge is a 6 month competition that starts in October and ends in March. In this competition, student teams from 54 universities across the world are competing to build a long-short, market neutral equity portfolio that would generate the most risk-adjusted return in the given time horizon while operating under a few specific portfolio constraints. Each team is ranked against each other based on risk-adjusted return and sharpe ratio. Our team consisted of 5 senior finance students at the University of Arizona. Together, we developed our own unique market outlook and portfolio strategy in order to successfully invest $1,000,000 in (hypothetical) capital. We used industry tilts towards financials, energy, and consumer discretionary sectors and factor tilts towards momentum and value stocks as our main drivers of return while minimizing market exposure by keeping our beta between -0.25 and +0.25. The University of Arizona finished the competition in first place in overall portfolio ranking with a return of 12.23% and in fifth place for sharpe ratio at 1.43.
    • 2017 Chicago Quantitative Alliance Investment Challenge: University of Arizona CQA Team – Investment Strategy

      Bateman, Spencer Michael (The University of Arizona., 2017)
      In order to complete my honors thesis in finance, I joined a team of five finance students in participating in the 2017 Chicago Quantitative Alliance Investment Challenge. The challenge required teams to create $2,000,000 market-neutral investment portfolios utilizing both long and short equity positions. From November 8th until March 31st, our team actively managed our equity portfolio by selecting stocks from a 1,000 stock investment universe, while 53 other teams from universities around the world competed against our portfolio using measures of absolute return, risk-adjusted return, and a team video explaining our performance and investment strategy. By utilizing a strategy contingent on both industry bets and style exposures to value and momentum, the University of Arizona team has achieved an absolute return of 12.23% and a Sharpe Ratio of 1.43.
    • 30/30 Museum & Park: Engaging Artifacts

      Kwolek, Queston Aureon (The University of Arizona., 2017)
      This project is located in the St. Henri neighborhood along the Lachine Canal in Montreal, Quebec. Industrial artifacts along the canal are culturally and historically significant to the people of Montreal. These artifacts are currently disconnected from public access – residents and tourists should be able to fully engage with them. The abandoned malting plant site has the potential to become an engaging destination that visitors want to explore. The proposal honors and reimagines the site’s industrial infrastructure and introduces valuable public amenities to the Lachine Canal. The 30/30 concept refers to the juxtaposition of the existing thirty silos and proposed thirty mounds. Generated from the volumetric capacity of the silos and natural form of grain, the mounds support vegetation to restore the sites pre-industrial presence of nature. Museum functions and public spaces are integrated into both the silos and mounds, resulting in an activity-driven experience for visitors that is centered on exploration and discovery. The proposal has the potential to host events, exhibitions, and outdoor activities year-round. By allowing guests to "trespass" through urban artifacts, they are invited to discover the mysterious atmosphere and cultural significance of the former factory and the site’s new public amenities.
    • 3D Printing of Mitral Valves for Pre-operative Medical Simulation

      Obafemi, Oluwatomisin Olurotimi (The University of Arizona., 2014)
    • 5-FU Chemotherapy Failure in Some Colorectal Cancer Patients with Microsatellite Instability

      Coggins, Si'Ana Apri (The University of Arizona., 2015)
      Human colorectal cancer (CRC) is the third most commonly diagnosed cancer as well as the second leading cause of cancer mortality in the United States. The hypothesis to be tested in this study is that the loss of TGFβ signaling causes overexpression of the uridine phosphorylase (UP) gene in human CRC when treated with 5-fluorouracil (5-FU), a common chemotherapeutic reagent. As a result, 5-FU may be metabolized via the RNA pathway, causing an increase in host-toxicity. Conversely, a mutation in the KRAS gene may drive the reaction towards the antitumor, DNA metabolic pathway. This mechanism would explain the ineffective nature of 5-FU-based treatments on tumors, some of which are TFGβ signaling-deficient, that are usually characterized as microsatellite instability high (MSI-H). If so, situational inhibition of UP may increase the intended anti-tumor activity of the 5-FU treatment while decreasing host-toxicity in this subcategory of MSI-H tumors, thus allowing only patients whose tumors have a 5-FU-susceptible genetic profile to be treated successfully with 5-FU based therapy. Cancerous cell lines containing different combinations of TGFBR2 and KRASᴳ¹³ᴰ mutations will be cultured and photographed. The cell lines Hke3 and Hkh2 contain a TGFBR2 mutation and have a morphological pattern that closely resembles the colonic mucosa while the HCT116 cell line contains both TGFBR2 and KRASᴳ¹³ᴰ mutations and has less structured morphology. Following culturing, UP and TP mRNA expression levels in all cell lines will be determined through reverse transcriptase (RT)-PCR and normalized to β-actin. If the hypothesis is supported, and then verified in patients, personalized therapy can be used to determine whether 5-FU should be administered in colorectal cancer cases in which KRASᴳ¹³ᴰ and TGFBR2 mutations are present or absent.
    • Abba! The Daddy Relationship God Wants with You

      Maakestad, Susan (The University of Arizona., 2013)
      This project is part of a longer book manuscript presenting an in-depth exploration of God’s expressed desire for a Daddy relationship with man. His desire for intimacy in his role as man’s heavenly father is presented in layman’s terms, illuminated with biblical texts and the writings of classical and contemporary authors. These texts reflect God’s desire to call him Abba, and this is a highly specialized term: "Abba is not Hebrew, the language of liturgy, but Aramaic, the language of home and everyday life … Abba is the intimate word of a family circle." - Thomas A. Smail, The Forgotten Father. A contextual base in the introductory chapter explores God’s covenant relationship with mankind while analyzing institutional obstacles that may impede the intimate parent-child relationship. The more informal tone in the remaining chapters draws parallels between earthly parents’ interaction with, training of and devotion to their own children, as the foundational claim that man is created in the image of God is applied to this setting and the argument for a similar interaction, training and devotion in a relationship between God the Father and his children is advanced and supported.
    • Above Below

      Canez, Katelyn Alane (The University of Arizona., 2015)
      Alix should have died years ago, her body ravaged by cancer. At fifteen, she's an anomaly among the Scavengers, who prowl the surface of war-ravaged Earth for scraps of the old world. When Above scientists capture Alix for medical testing, no one is sure that she will ever come back. A year later, she escapes, desperate to regain her old life-but friends have changed, loyalties have changed, and she has changed. Alix must find a way to blend old and new experiences together while outrunning the clutches of the scientists. No longer a child of Below, a fugitive of Above, she belongs to two worlds, both of which clamor to claim her as their own. A dystopian novel that asks what it means to grow up in a world full of flaws - this is Above Below.
    • Acanthosis Nigricans: A Risk Factor for Type II Diabetes

      Eidson, Andrea Christine (The University of Arizona., 2017)
      This paper serves as a review of Type II diabetes and pre-diabetes and their associated risk factors: obesity, race, age, and family history of the disease. A new risk factor, Acanthosis Nigricans, is examined in ordinance with common diabetes risk factors, and correlations are drawn between its occurrence and Type II diabetes. Acanthosis Nigricans is a skin condition that can be non-invasively identified. With the current rise of diabetes and obesity in children and adults, finding an easily identifiable risk factor is pertinent for catching the disease in the pre-diabetic state before Type II diabetes is developed. The role of Community Health Workers in disease prevention and intervention was also examined. In our findings, Acanthosis Nigricans is indicative specifically of development of insulin resistance and is most often seen in Hispanic and Black populations. Decreases in physical activity and increases in food-insecure households puts children at higher risk of diabetes development than ever before. Community Health Workers serve as a critical link between families in low-income communities and adequate health education. With proper training, community health workers have the potential to help low-income families stop the development of Type II diabetes in their children before it begins.
    • Accelerator Mass Spectrometry: A Video Tour of the Carbon-14 Dating Process

      Genovese, Taylor Robert (The University of Arizona., 2013)
      The purpose of this project is to create a video that engages and informs an undergraduate audience about the Carbon-14 dating process. The video takes you through the history of the Accelerator Mass Spectrometry Lab at the University of Arizona as well as discussion of what exactly carbon-dating is. The audience is then given a walking tour of the actual accelerator while the steps of Carbon-14 dating are explained.