• The 150-Hour Rule: How Policy Decisions Affect the Supply of Public Accountants

      McLeod, Martha Lamb (The University of Arizona., 2011-05)
    • 17β Estradiol Decreases Vasodilation at 31°C in Ovariectomized Rats

      Brown, Jessica Nicole (The University of Arizona., 2010-05)
      The purpose of this Honor's Thesis is to investigate rat heat dissipation in correlation with estradiol (commonly referred to as estrogen) at different environmental (ambient) temperatures. The relevance of this study is investigative of post-menopausal hot flushes as a thermoregulatory dysfunction.
    • The 1979 Iranian revolution: the revolutionary revolution

      Brandis, Dov Asher (The University of Arizona., 2009-05)

      Hsu, Ivann Hong; Emerson, Joanna; Wong, Andrew; Zinsli, Phillip (The University of Arizona., 2009-05)

      Zinsli, Phillip Alexander (The University of Arizona., 2009-05)

      Emerson, Joanna Louise (The University of Arizona., 2009-05)
    • The 2012 Presidential Election Gender Gap

      Caicedo, Andrea (The University of Arizona., 2015)
      The gender gap in presidential elections has been an important part of American politics for the past decades. This phenomenon in politics refers to the differences of men and women in party identification and voting behavior. This paper explains the origins of the gender gap dating back to the 1980s. It explains the patterns and analyzes the most significant issues in each presidential election. Finally, it analyzes the gender gap in the 2012 presidential election. It focuses on the issues that had the biggest difference and it explains why some issues are more susceptible to having a greater gender gap.

      LEISTER, DAVID EDWARD (The University of Arizona., 2016)
      The American Society of Mechanical Engineers (ASME) hosts the annual Human Powered Vehicle Challenge (HPVC), in which student design teams from universities and colleges around the world design, build, and compete human powered vehicles. A human powered vehicle is just any vehicle whose motive power comes from the exertion of its driver(s). The University of Arizona’s (UA) entry in the 2016 HPVC West, Magnum, succeeds Blue Steel (2013), Le Tigre (2014), and Ferrari (2015). It is the most ambitious project undertaken by the UA human powered vehicle team, featuring a carbon fiber/aluminum hybrid frame and full fairing, and a custom built steering system. An onboard electronics suite includes turn signals, a traffic horn, and a novel Roll Alert System, an Android app developed by the team to alert everyone in the event of a vehicle rollover or crash. Both the mechanical and electronic systems were designed and built from the ground up by this year’s team. Magnum is also the best-performing UA human powered vehicle in recent history, earning Top 10 ranks in the 2016 HPVC West’s Design and Innovation categories, and 13th overall.

      CARLSON, JONATHAN ANDERS (The University of Arizona., 2016)
      For my finance, honors thesis I participated in the 4th annual CQA Investment Challenge. The goal of the challenge is to successfully manage an equity long-short, market neutral portfolio (hedge fund). I worked on a team with three other guys from the Applied Portfolio Management class to invest and manage $20,000,000 of hypothetical money. Our investment horizon ran from October 30, 2015 – April 1, 2016. The stock universe we had access to was the Russell 1000, which mainly consists of the highest-ranking large cap stocks in the US equity market. Thirty-one teams from different universities were judged at the end of the competition on absolute return rank, adjusted return rank (the Sharpe ratio) and evaluation of the team video, which discussed investment strategy. The University of Arizona team achieved an absolute return of 6.47%, Sharpe ratio of 0.36 and abnormal return (alpha) of 20.05%. We finished with a ranking of 7th place out of 31 participating schools.
    • 2017 Chicago Quantitative Alliance Investment Challenge: University of Arizona CQA Investment Strategy

      To, Kham Hong; Hascalovici, Hilla; Bateman, Spencer; Recchion, Edward; Recchion, Charles (The University of Arizona., 2017)
      The CQA challenge is a 6 month competition that starts in October and ends in March. In this competition, student teams from 54 universities across the world are competing to build a long-short, market neutral equity portfolio that would generate the most risk-adjusted return in the given time horizon while operating under a few specific portfolio constraints. Each team is ranked against each other based on risk-adjusted return and sharpe ratio. Our team consisted of 5 senior finance students at the University of Arizona. Together, we developed our own unique market outlook and portfolio strategy in order to successfully invest $1,000,000 in (hypothetical) capital. We used industry tilts towards financials, energy, and consumer discretionary sectors and factor tilts towards momentum and value stocks as our main drivers of return while minimizing market exposure by keeping our beta between -0.25 and +0.25. The University of Arizona finished the competition in first place in overall portfolio ranking with a return of 12.23% and in fifth place for sharpe ratio at 1.43.
    • 2017 Chicago Quantitative Alliance Investment Challenge: University of Arizona CQA Team – Investment Strategy

      Bateman, Spencer Michael (The University of Arizona., 2017)
      In order to complete my honors thesis in finance, I joined a team of five finance students in participating in the 2017 Chicago Quantitative Alliance Investment Challenge. The challenge required teams to create $2,000,000 market-neutral investment portfolios utilizing both long and short equity positions. From November 8th until March 31st, our team actively managed our equity portfolio by selecting stocks from a 1,000 stock investment universe, while 53 other teams from universities around the world competed against our portfolio using measures of absolute return, risk-adjusted return, and a team video explaining our performance and investment strategy. By utilizing a strategy contingent on both industry bets and style exposures to value and momentum, the University of Arizona team has achieved an absolute return of 12.23% and a Sharpe Ratio of 1.43.
    • 30/30 Museum & Park: Engaging Artifacts

      Kwolek, Queston Aureon (The University of Arizona., 2017)
      This project is located in the St. Henri neighborhood along the Lachine Canal in Montreal, Quebec. Industrial artifacts along the canal are culturally and historically significant to the people of Montreal. These artifacts are currently disconnected from public access – residents and tourists should be able to fully engage with them. The abandoned malting plant site has the potential to become an engaging destination that visitors want to explore. The proposal honors and reimagines the site’s industrial infrastructure and introduces valuable public amenities to the Lachine Canal. The 30/30 concept refers to the juxtaposition of the existing thirty silos and proposed thirty mounds. Generated from the volumetric capacity of the silos and natural form of grain, the mounds support vegetation to restore the sites pre-industrial presence of nature. Museum functions and public spaces are integrated into both the silos and mounds, resulting in an activity-driven experience for visitors that is centered on exploration and discovery. The proposal has the potential to host events, exhibitions, and outdoor activities year-round. By allowing guests to "trespass" through urban artifacts, they are invited to discover the mysterious atmosphere and cultural significance of the former factory and the site’s new public amenities.
    • 3D Printing of Mitral Valves for Pre-operative Medical Simulation

      Obafemi, Oluwatomisin Olurotimi (The University of Arizona., 2014)
    • 5-FU Chemotherapy Failure in Some Colorectal Cancer Patients with Microsatellite Instability

      Coggins, Si'Ana Apri (The University of Arizona., 2015)
      Human colorectal cancer (CRC) is the third most commonly diagnosed cancer as well as the second leading cause of cancer mortality in the United States. The hypothesis to be tested in this study is that the loss of TGFβ signaling causes overexpression of the uridine phosphorylase (UP) gene in human CRC when treated with 5-fluorouracil (5-FU), a common chemotherapeutic reagent. As a result, 5-FU may be metabolized via the RNA pathway, causing an increase in host-toxicity. Conversely, a mutation in the KRAS gene may drive the reaction towards the antitumor, DNA metabolic pathway. This mechanism would explain the ineffective nature of 5-FU-based treatments on tumors, some of which are TFGβ signaling-deficient, that are usually characterized as microsatellite instability high (MSI-H). If so, situational inhibition of UP may increase the intended anti-tumor activity of the 5-FU treatment while decreasing host-toxicity in this subcategory of MSI-H tumors, thus allowing only patients whose tumors have a 5-FU-susceptible genetic profile to be treated successfully with 5-FU based therapy. Cancerous cell lines containing different combinations of TGFBR2 and KRASᴳ¹³ᴰ mutations will be cultured and photographed. The cell lines Hke3 and Hkh2 contain a TGFBR2 mutation and have a morphological pattern that closely resembles the colonic mucosa while the HCT116 cell line contains both TGFBR2 and KRASᴳ¹³ᴰ mutations and has less structured morphology. Following culturing, UP and TP mRNA expression levels in all cell lines will be determined through reverse transcriptase (RT)-PCR and normalized to β-actin. If the hypothesis is supported, and then verified in patients, personalized therapy can be used to determine whether 5-FU should be administered in colorectal cancer cases in which KRASᴳ¹³ᴰ and TGFBR2 mutations are present or absent.

      Newberry, Eric Evan Michael (The University of Arizona., 2018)
      The Hadoop Distributed File System (HDFS) is a distributed le system used to support multiple widely-used big data frameworks, including Apache Hadoop and Apache Spark. Since these frameworks are often run across many compute nodes, it is possible that multiple nodes will read the same data. In addition, since data is replicated across multiple nodes for storage, the same data will be written multiple times across the network. In this paper, we conduct an evaluation of the caching potential present in HDFS in order to determine if in-network caching, particularly of the type seen in Named Data Networking (NDN), would reduce the amount of tra c seen in a Spark cluster network, as well as the average load on each data storage node. Our results show that for most benchmarks running on Apache Spark, a majority of the large read operations were done to transfer the Spark and application dependency libraries to each compute node. In addition, there was not a signi cant amount of read tra c in the network for most of the applications we evaluated, making the bene ts of in-network caching for HDFS questionable.
    • A Classical Insight Into the Separation Between Church and State

      Videla, Gabrielle Marie (The University of Arizona., 2018)
      This paper connects events of the late Roman Republic with the United States of America’s principle of separation of Church and State. Many scholars find similarities between the Roman Republic and the U.S., but do not know the depth of connection or how the founding of the nation was impacted by the classical world. In the first sections of this paper I define the Roman state cult and examples of how it was abused during the turbulence of the late Republic. The next section describes the classical education the Founding Fathers received. There follows an indepth explanation of the creation and support of the principle of separating church and state during the founding of the United States. To conclude, connections are drawn between that principle of separation and the troubling events of the late Roman Republic that the Founding Fathers would have read from classical authors. It is hoped that this paper shows how a study of the classical world offers modern scholars a chance to understand the modern world.

      Okuagu, Ashley Chisom (The University of Arizona., 2018)
      Racial/ethnic sleep disparities have been documented for decades and may be related to discrimination faced at various levels, both in individual communities and at the sociopolitical stratosphere. The purpose of this research was to delve into a specific demographic of the national population, college/university students, and analyze whether the predominance of white students at various institutions affected the sleep quality and duration of minority students. Data used in this research was collected by the American College Health Association (ACHA) National College Health Assessment. In this survey, students identified as Non-Hispanic White, Black/African-American, Hispanic/Latino, Asian, Native American, Multiracial, or Other. Schools where the majority of respondents were Non-Hispanic White were classified as “Majority-White” schools while schools where a majority of the respondents were not Non-Hispanic White were classified as “Majority-Minority” schools. The results showed an overall correlation with poorer sleep in minority students at Majority-White schools and no association between school type and sleep sufficiency in Hispanics/Latinos. Sociopolitical and socioenvironmental influences may be involved, though future directions for this study may include further analysis on the reasoning behind the results of this study.
    • A Design Space to Amplify Playtime as a Foundation for Inclusivity

      Colantuoni, Carolina Alicia (The University of Arizona., 2018)
      Playtime has a vital role in children’s development. Personal growth and the evolution relationships within their lives highly depends on they way they perceive, interact and experience the world. Through play, children are able to explore their surroundings, each other and themselves in a safe environment. There is an opportunity to use this crucial time in children lives to introduce diversity and prevent exclusivity from increasing as they age. To reach an inclusive future, design can be employed to create an experience for children of diverse backgrounds, abilities and cultures to connect to one another, learn about each other and form the foundations for understanding. To amplify playtime, the needs of children around the ages of 6-8 must be taken into consideration as well as all accessibility needs for those with different physical abilities or language barriers. This project explores the design thinking method and how visual communications comes alongside the design thinking process to speak of values and ideals. A visual language and game, that stems from a core mission statement, has been created for a fictional company. In the future, the game could carry in to tools, like an app, to carry on the learning experience and provide other environments for connection.

      Clark, Alexis Elizabeth (The University of Arizona., 2018)
      Because of the 5.8 billion individuals in the world engage in religious practice, it is important to know how religiosity and religious practices affect the neuroanatomy and neurophysiology of an individual. This fact is only enhanced by the fact that these numbers are expected to rise by 32% by 2060, according to a 2015 Pew Research study. 29By noting the various neurophysiologies between those who are religious and nonreligious, society can better understand the psychological processing that goes behind groups forming political policy, health care systems, and humanitarian efforts. Within this literature review, I research how genetic predisposition can impact associated religious affiliation, what influence spiritual experience has on the brain and how religious affiliation, or lack thereof, can mean for individual behavioral tendencies. The review concludes that there is a plethora of data showing both how religion affects the brain and how the genetically predisposed brain structure can influence religious practice.

      Shaw, Karrol Anne (The University of Arizona., 2018)
      Cancer is currently the second leading cause of death in the United States, and is expected to surpass heart disease as the leading cause in the coming years. Recent research has suggested that adhering to a whole-foods plant-based diet high in fruits, vegetables and unrefined grains, and low in red meat, processed meat, refined grains and added sugars, can assist in the prevention of cancer onset and recurrence. This analysis will explore dietary risk factors associated with the initiation, promotion, and progression of cancer, as well as certain components of a plant-based diet that can aid in the prevention of various types of cancer. An extensive body of evidence in the literature supports the finding that a plant-based diet composed of whole plant foods, in contrast to the traditional western diet high in meat, processed food, and dietary fat, can significantly reduce the risk of developing cancer. For example, a plant-based diet has been shown to positively affect survival rates in colorectal, breast, and prostate cancer. Further studies will need to be conducted in an effort to validate the findings that support the adoption of a whole-foods plant-based diet in the prevention of cancer onset and recurrence.