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    A NOVEL RESUSCITATION ALGORITHM USING WAVEFORM ANALYSIS AND END-TIDAL CARBON DIOXIDE PRESSURE FOR VENTRICULAR FIBRILLATION

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    Author
    Chaudhry, Fahd Abdullah
    Issue Date
    2011
    Keywords
    Amplitude-spectrum area
    Cardiac arrest
    End-tidal carbon dioxide
    Resuscitation
    Ventricular fibrillation
    Advisor
    Indik, Julia H
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    Ventricular fibrillation (VF) is a lethal heart rhythm that leads to cardiac arrest. It has been shown that amplitude spectral area (AMSA) in prolonged VF correlates with success of resuscitation. This study will compare traditional resuscitation with a novel resuscitation algorithm using AMSA and end-tidal carbon dioxide (ETCO2) to time defibrillations.VF will be induced in 60 swine. Resuscitation will commence after 10 minutes of untreated VF. Cases will receive defibrillation if AMSA is >19.8 mVHz and ETCO2 >20 mm of Hg, otherwise chest compressions will continue for another 90 seconds. Controls will have standard resuscitation. Sub group analysis will include effect of induced myocardial infarction (MI).End points will include survival, neurologic scores, duration of resuscitation efforts, and number of defibrillations.This experiment will establish whether using AMSA and ETCO2 to time defibrillations results in superior resuscitation compared with standard techniques.
    Type
    Electronic Thesis
    text
    Degree Name
    M.S.
    Degree Level
    masters
    Degree Program
    Graduate College
    Biomedical Engineering
    Degree Grantor
    University of Arizona
    Collections
    Master's Theses

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