Molecular Understanding of Selected Autoimmune Diseases

Abstract

Pathogens that affect the immune system, or defects in the immune system contribute to numerous autoimmune diseases. In this paper, we are going to review, analyze and understand recent findings in literature. The papers that are to be reviewed explore the observation of loss of regulatory T cells in individuals with multiple sclerosis, the importance of CD4+ during HIV infection, the role of CCR6 in the immune system and the importance of Pan-DR-Binding Hsp60 self-epitopes in rheumatoid arthritis. So this literary review is limited to understanding major defects in specific parts of the immune system and its role in causing the specific autoimmune disease. The reason for this focus is to highlight the importance of the immune system in the functioning of many processes in our body and more specifically the importance of T cells and its regulators in maintaining the immune system.