• Login
    View Item 
    •   Home
    • UA Graduate and Undergraduate Research
    • UA Theses and Dissertations
    • Dissertations
    • View Item
    •   Home
    • UA Graduate and Undergraduate Research
    • UA Theses and Dissertations
    • Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UA Campus RepositoryCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournal

    My Account

    LoginRegister

    About

    AboutUA Faculty PublicationsUA DissertationsUA Master's ThesesUA Honors ThesesUA PressUA YearbooksUA CatalogsUA Libraries

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Depression and cognitive deterioration in the elderly: A follow-up study.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    azu_td_9208027_sip1_m.pdf
    Size:
    3.775Mb
    Format:
    PDF
    Description:
    azu_td_9208027_sip1_m.pdf
    Download
    Author
    Nussbaum, Paul David.
    Issue Date
    1991
    Keywords
    Older people -- Psychology
    Depression in old age -- Case studies
    Cognition in old age -- Case studies.
    Advisor
    Kaszniak, Alfred W.
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    The extent of cognitive deficit in depressed elderly remains unclear. Recent follow-up studies of elderly patients diagnosed as depressed suggest that depression may present as the initial sign of progressive dementia. This raises questions regarding the nature of the depression in those individuals who deteriorate cognitively over time, and encourages the search for clinical indicators of those depressed who are likely to deteriorate. Thirty-five depressed older adult outpatients were comprehensively examined and re-evaluated with a brief neuropsychological battery after one or more years. Twenty-three probable dementia of the Alzheimer's type patients (DAT) provided a comparison with a known progressive disorder. Patients with a decline of four points from their original score on a mental status examination comprised the "depressed with cognitive deterioration" sample (N = 8) and all others made up the "depressed without cognitive deterioration" sample (N = 27). These two samples were then compared on clinical variables from the initial neuropsychological, medical, radiological, and patient history examination. A Multivariate analysis of variance using the following variables: initial age, education, modified Hachinski, initial Mini-Mental State, Wechsler Memory Quotient, vocabulary, digit span, similarities, picture completion, block design, and digit symbol subtests of the Wechsler Adult Intelligence Scale-Revised, initial Geriatric Depression Scale, and Grocery Store Test of verbal fluency failed to differentiate those depressed elderly that declined from those who did not. A series of Chi-square analyses using the medical and radiological variables demonstrated a significant association between depressed with deterioration and magnetic resonance imaging (MRI) abnormalities, computerized tomography (CT) abnormalities, and Electrocardiogram (EKG) abnormalities. Those depressed patients with cognitive deterioration demonstrated a higher frequency of white matter abnormalities on the combined CT and MRI than did those depressed patients with no deterioration. Leuko-araiosis in depressed elderly may represent a clinical marker for the identification of later cognitive deterioration. Results indicate: (1) a need for the development of more sensitive neuropsychological measures for accurate prediction of deterioration; (2) the importance of follow-up neuropsychological evaluations on depressed elderly; (3) relationship between white matter abnormality and cognitive deterioration in depressed elderly, and (4) support for the hypothesis that depression may present as an early sign of a later developing progressive dementia.
    Type
    text
    Dissertation-Reproduction (electronic)
    Degree Name
    Ph.D.
    Degree Level
    doctoral
    Degree Program
    Psychology
    Graduate College
    Degree Grantor
    University of Arizona
    Collections
    Dissertations

    entitlement

     
    The University of Arizona Libraries | 1510 E. University Blvd. | Tucson, AZ 85721-0055
    Tel 520-621-6442 | repository@u.library.arizona.edu
    DSpace software copyright © 2002-2017  DuraSpace
    Quick Guide | Contact Us | Send Feedback
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.