The UA Campus Repository is experiencing systematic automated, high-volume traffic (bots). Temporary mitigation measures to address bot traffic have been put in place; however, this has resulted in restrictions on searching WITHIN collections or using sidebar filters WITHIN collections. You can still Browse by Title/Author/Year WITHIN collections. Also, you can still search at the top level of the repository (use the search box at the top of every page) and apply filters from that search level. Export of search results has also been restricted at this time. Please contact us at any time for assistance - email repository@u.library.arizona.edu.
PROGRESS TOWARDS A SYNTHESIS OF DEOXYBOUVARDIN AND ANALOGUES; NEW SYNTHETIC METHODS.
| dc.contributor.author | JANDA, KIM DAVID. | |
| dc.creator | JANDA, KIM DAVID. | en_US |
| dc.date.accessioned | 2011-10-31T18:54:24Z | |
| dc.date.available | 2011-10-31T18:54:24Z | |
| dc.date.issued | 1984 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10150/187884 | |
| dc.description.abstract | This work involved synthetic approaches to the anti-tumor agent deoxybouvardin. Numerous reactions were explored in an attempt to build an amino acid from an aromatic aldehyde under mild conditions. From these reactions new and useful synthetic methods have been discovered for making α-acylamino alcohols and unsymmetrical imides. Some dehydroamino acids were successfully prepared from aromatic aldehydes and an N-acylphosphorylglycine ester. Progress towards a synthesis of 5- η-thiodeoxybouvardin will also be discussed. | |
| dc.language.iso | en | en_US |
| dc.publisher | The University of Arizona. | en_US |
| dc.rights | Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. | en_US |
| dc.subject | Amino acids -- Synthesis. | en_US |
| dc.subject | Organic compounds -- Synthesis. | en_US |
| dc.title | PROGRESS TOWARDS A SYNTHESIS OF DEOXYBOUVARDIN AND ANALOGUES; NEW SYNTHETIC METHODS. | en_US |
| dc.type | text | en_US |
| dc.type | Dissertation-Reproduction (electronic) | en_US |
| dc.identifier.oclc | 693569290 | en_US |
| thesis.degree.grantor | University of Arizona | en_US |
| thesis.degree.level | doctoral | en_US |
| dc.identifier.proquest | 8505232 | en_US |
| thesis.degree.discipline | Chemistry | en_US |
| thesis.degree.discipline | Graduate College | en_US |
| thesis.degree.name | Ph.D. | en_US |
| refterms.dateFOA | 2018-08-14T13:51:42Z | |
| html.description.abstract | This work involved synthetic approaches to the anti-tumor agent deoxybouvardin. Numerous reactions were explored in an attempt to build an amino acid from an aromatic aldehyde under mild conditions. From these reactions new and useful synthetic methods have been discovered for making α-acylamino alcohols and unsymmetrical imides. Some dehydroamino acids were successfully prepared from aromatic aldehydes and an N-acylphosphorylglycine ester. Progress towards a synthesis of 5- η-thiodeoxybouvardin will also be discussed. |
Files in this item
Name:
azu_td_8505232_sip1_m.pdf
Size:
1.468Mb
Format:
PDF
Description:
azu_td_8505232_sip1_m.pdf