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dc.contributor.advisorOland, Lynne A.en_US
dc.contributor.authorChandler, Larry
dc.creatorChandler, Larryen_US
dc.date.accessioned2011-12-05T14:13:37Z
dc.date.available2011-12-05T14:13:37Z
dc.date.issued2008en_US
dc.identifier.urihttp://hdl.handle.net/10150/193321
dc.description.abstractThe moth Manduca sexta has been a common model for the study of the insect olfactory systems. The neuronal architecture in the antennal lobes (ALs) of insects and in the olfactory lobes of vertebrates is similar in structure and development. In Manduca, as in other olfactory systems, sensory receptor neurons send axons into the AL where they form synapses with local interneurons (LNs) and projection neurons (PNs) within the structural units of glomeruli. Here, I present the morphological development of one type of interneuron, the uniglomerular projection neuron (uPN), in normal AL development and in AL development in the absence of olfactory receptor neurons (ORNs). Using fluorescent-dye labeling of uPNs and confocal microscopy, my results show that in the absence of ORNs, uPN dendritic arborization is uncharacteristic of that in normally developing ALs, reinforcing the concept that afferent input guides the development of architecture in sensory areas of the brain.
dc.language.isoENen_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.subjectprojection neuronsen_US
dc.subjectolfactory lobeen_US
dc.subjectManduca sextaen_US
dc.titleMorphological Development of Uniglomerular Projection Neurons in the Olfactory Lobe of the Moth, Manduca sextaen_US
dc.typetexten_US
dc.typeElectronic Thesisen_US
dc.contributor.chairTolbert, Leslie P.en_US
dc.identifier.oclc659749779en_US
thesis.degree.grantorUniversity of Arizonaen_US
thesis.degree.levelmastersen_US
dc.contributor.committeememberStrausfeld, Nicholas J.en_US
dc.identifier.proquest2748en_US
thesis.degree.disciplineEcology & Evolutionary Biologyen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.nameMSen_US
refterms.dateFOA2018-07-14T11:44:24Z
html.description.abstractThe moth Manduca sexta has been a common model for the study of the insect olfactory systems. The neuronal architecture in the antennal lobes (ALs) of insects and in the olfactory lobes of vertebrates is similar in structure and development. In Manduca, as in other olfactory systems, sensory receptor neurons send axons into the AL where they form synapses with local interneurons (LNs) and projection neurons (PNs) within the structural units of glomeruli. Here, I present the morphological development of one type of interneuron, the uniglomerular projection neuron (uPN), in normal AL development and in AL development in the absence of olfactory receptor neurons (ORNs). Using fluorescent-dye labeling of uPNs and confocal microscopy, my results show that in the absence of ORNs, uPN dendritic arborization is uncharacteristic of that in normally developing ALs, reinforcing the concept that afferent input guides the development of architecture in sensory areas of the brain.


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