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AbstractSeventeen herbicides recently gaining registrations in corn, soybeans, or other major crops were evaluated in screening tests for potential use in melons. In a preemergence herbicide screening test, flumioxazin, dimethenamid, halosulfuron, and s-metolachlor demonstrated melon crop safety at rates higher than rates for effective weed control. In a postemergence screening test, halosulfuron and rimsulfuron gave acceptable weed control with adequate crop safety. Flumetsulam and thifensulfuron appeared to offer some acceptable weed control with a very narrow margin of crop safety. Herbicides that did not offer adequate melon crop safety or acceptable weed control in the screening tests were carfentrazone, sulfentrazone, cloransulam, flumiclorac, fluthiamide/metribuzin, imazamox, isoxaflutole, triflusulfuron, primisulfuron/prosulfuron, and clomazone.