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dc.contributor.authorTakyar, Ankit
dc.creatorTakyar, Ankiten_US
dc.date.accessioned2013-03-12T18:06:09Z
dc.date.available2013-03-12T18:06:09Z
dc.date.issued2012
dc.identifier.citationTakyar, Ankit. (2012). Identifying Potential Candidate SNP's and Genes Linked to Handedness for Future Study (Bachelor's thesis, University of Arizona, Tucson, USA).
dc.identifier.urihttp://hdl.handle.net/10150/271944
dc.description.abstractThe goal was to identify genes for future study that might be linked to handedness for potential candidate gene study. We were able to find 3 major genes through statistically analyzing SNP data within a Genome-wide association Statistical Analysis tool, PLINK. 27 SNPs were chosen based on P-values of below .001, further analysis was done to these 27 SNPs to figure out their gene locus. Using NCBI we found 21 SNPs were within a gene locus. A total of 16 genes were found from the 21 SNPs that were located within a gene locus. Three extra genes were examined since they were located in a gene of interest CTNNA2. The genes found were further screened for high expression in subcortical regions and that have been implicated in neural function or brain development. Out of the 17 genes determined, IRAK2, NRG1, and CTNNA2 adhered to the criteria for screening.
dc.language.isoenen_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleIdentifying Potential Candidate SNP's and Genes Linked to Handedness for Future Studyen_US
dc.typetexten_US
dc.typeElectronic Thesisen_US
thesis.degree.grantorUniversity of Arizonaen_US
thesis.degree.levelbachelorsen_US
thesis.degree.disciplineHonors Collegeen_US
thesis.degree.disciplineMolecular and Cellular Biologyen_US
thesis.degree.nameB.S.en_US
refterms.dateFOA2018-08-27T02:04:42Z
html.description.abstractThe goal was to identify genes for future study that might be linked to handedness for potential candidate gene study. We were able to find 3 major genes through statistically analyzing SNP data within a Genome-wide association Statistical Analysis tool, PLINK. 27 SNPs were chosen based on P-values of below .001, further analysis was done to these 27 SNPs to figure out their gene locus. Using NCBI we found 21 SNPs were within a gene locus. A total of 16 genes were found from the 21 SNPs that were located within a gene locus. Three extra genes were examined since they were located in a gene of interest CTNNA2. The genes found were further screened for high expression in subcortical regions and that have been implicated in neural function or brain development. Out of the 17 genes determined, IRAK2, NRG1, and CTNNA2 adhered to the criteria for screening.


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