EXERCISE RESPONSE TO ACUTE AND CHRONIC BETA BLOCKADE IN HEALTHY MALE SUBJECTS
Publisher
The University of Arizona.Rights
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.Abstract
The purpose of this study was to examine exercise responses during acute and chronic administration of BB, Beta Blockade. Twenty-eight healthy males performed maximal treadmill exercise tests after 1 day and 9 days of 3 double-blind, randomized conditions: a placebo (Pl), propanolol (Pr) 80 mg bid, and atenolol (At) 100 mg daily. Maximal heart rate (HR), oxygen consumption (VO₂), ventilation (VE), and treadmill time (TT) were significantly reduced by Pr and At after an acute and chronic dose. An acute dose of Pr and At caused a greater decrease in maximal HR compared to chronic administration (143.1 ± 5.0 b min⁻¹ at day 1 vs. 147.7 ± 4.2 b min⁻¹ at day 9). However, the overall exercise response was not effected by the change in HR in either the TR or UT subjects. These data indicate that there is no difference in exercise response to acute and chronic BB in young healthy males. (Abstract shortened with permission of author.)Type
textThesis-Reproduction (electronic)
Degree Name
M.S.Degree Level
mastersDegree Program
Graduate CollegeExercise and Sport Sciences