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    Metabolism and penetration of permethrin in resistant and susceptible strains of tobacco budworm, Heliothis virescens (F)

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    Author
    Kelly, Suzanne Eleanor, 1960-
    Issue Date
    1988
    Keywords
    Heliothis zea.
    Pyrethroids.
    Advisor
    Watson, Theo F.
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    A laboratory selected strain of Heliothis virescens demonstrating a 400-fold resistance to permethrin exhibited no differences in penetration and only a slight enhancement of metabolism when compared with a susceptible strain. Synergism with piperonyl butoxide and DEF produced similar synergist ratios for the resistant and susceptible strains, but the resistant strain showed a much larger synergist difference. Thin layer chromatography of extracts from larvae dosed with 14C-labelled permethrin demonstrated a small increase in metabolism of the cis-isomer by the resistant strain, but no differences in metabolism of the trans-isomer. The synergism study and the 14C-labelled permethrin experiment both indicate that there is a small increase in metabolism of permethrin in the resistant strain, but not enough to account for the greatly increased LD50 value. Cross-resistance to DDT indicated that target site insensitivity may play a major role in resistance to pyrethroids in this strain.
    Type
    text
    Thesis-Reproduction (electronic)
    Degree Name
    M.S.
    Degree Level
    masters
    Degree Program
    Graduate College
    Entomology
    Degree Grantor
    University of Arizona
    Collections
    Master's Theses

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