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    Additional indications for genetic counseling in women of advanced maternal age

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    Author
    Hays, Francis Myron, 1963-
    Issue Date
    1988
    Keywords
    Genetic counseling.
    Maternal age.
    Pregnancy in middle age.
    Advisor
    Hoyme, H. Eugene
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    Genetic counseling for women with advanced maternal age is well established medical standard of care. However, only one study has yet been done to test the validity of that policy. Records of 283 patients referred for genetic counseling with advanced maternal age as a primary indication were examined. Of these, 57.6% had at least one additional indication. This value did differ significantly from Rubin's data which reported a 43.3% rate (X2 = 13.01, p > 0.001). The additional indications were broken down according to McKusick's system, and a statistical difference between my and Rubin's data was found in the autosomal dominant, autosomal recessive, potential teratogenic exposure and miscellaneous categories. There was no significant statistical difference between my and Rubin's data in the X-linked, chromosomal anomalies and multifactorial groups. These data underscore the need for physicians to refer patients with advanced maternal age for genetic counseling, and provides a scientific basis for doing so.
    Type
    text
    Thesis-Reproduction (electronic)
    Degree Name
    M.S.
    Degree Level
    masters
    Degree Program
    Graduate College
    Genetics
    Degree Grantor
    University of Arizona
    Collections
    Master's Theses

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