Preoperative nonparticulate antacid therapy: A comparison of Bicitra and Alka-Seltzer effervescent
KeywordsHealth Sciences, Pharmacology.
Health Sciences, Medicine and Surgery.
Health Sciences, Nursing.
MetadataShow full item record
PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
AbstractPulmonary damage resulting from aspiration of gastric contents has been reported to be related to the acidity of the aspirate. The purpose of this research was to evaluate if Alka-Seltzer Effervescent and/or Bicitra, ingested preoperatively, increased gastric pH >2.5 and if so, which of the two products sustained the increase for the greatest length of time. Twenty-nine subjects ingested either Alka-Seltzer Effervescent (n = 15) or Bicitra (n = 14) during the immediate preoperative period. Gastric pH was analyzed at 30 and 60 minutes post-ingestion via oro- or naso-gastric tube. Repeated measures Analysis of Variance demonstrated that both antacids elevated gastric pH >2.5 at 30 and 60 minutes post-ingestion. However, Alka-Seltzer Effervescent produced a statistically significant greater (p =.032) increase in gastric pH than Bicitra at both 30 and 60 minutes post-ingestion.
Degree ProgramGraduate College