Non-invasive detection of full-filling in the symbion artificial heart and ventricular assist devices
AdvisorMylrea, Kenneth C.
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PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
AbstractThe anatomy and physiology of the human heart, the historical development of heart transplantation and mechanical assistance, and total artificial heart and ventricular assist device systems are discussed. The focus of the investigation is on the detection of waveform indicators corresponding to full-filling of the artificial heart and ventricular assist device chambers. The developed software monitors the drive pressure waveform produced by the circulatory assist system until a full-fill indicator is detected. The event is verified by the detection of a corresponding indication during the same period within the flow waveform of the circulatory assist system. The appropriate alarm (for the right or left chamber) is updated each time a full-fill event is verified. When the user specified alarm limit is reached, an entry describing the alarm event is entered into the patient data file and a +5 volt analog signal is made available for external alarm activation.