Efficient sampling for dynamic single-photon emission computed tomographic imaging

Abstract

Our goal is to develop a single-photon emission computed tomography (SPECT) system for dynamic cardiac imaging so that heart disease may be more accurately evaluated. We have developed multiple, stationary, modular scintillation cameras that allow for dynamic imaging because of large detector area, large collection efficiency, high count-rate capability, and no motion of detector, collimator, or aperture. We make use of coded-aperture pinhole arrays because they increase photon-collection efficiency. The coded apertures allow for overlapping projections or multiplexing of an object onto the detector face. We have designed a novel collimation system that allows for an increased number of pinhole projections without substantial multiplexing. This new method is called "subslicing". We verified the subslice concept both in computer simulation and with our 16-module ring imaging system. Comparison of results with and without subslicing shows that the new approach substantially reduces artifacts in the image reconstruction. (Abstract shortened with permission of author.)