Glycosylations via in situ formation of glycosyl iodides from glycosyl bromides
| dc.contributor.advisor | Gervay-Hague, Jacquelyn | en_US |
| dc.contributor.author | Lam, Son Ngoc | |
| dc.creator | Lam, Son Ngoc | en_US |
| dc.date.accessioned | 2013-04-03T13:36:01Z | |
| dc.date.available | 2013-04-03T13:36:01Z | |
| dc.date.issued | 2001 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10150/278767 | |
| dc.description.abstract | Glycosyl iodides have proven to be highly efficient and stereospecific glycosyl donors. Unfortunately with such high reactivity, they possess short shelf lives. Glycosyl bromides, on the other hand, are more robust than their iodo-counterparts. But, glycosylations using glycosyl bromides in the absence of Lewis acid catalysts are slow. Recently, we have demonstrated conditions augmenting glycosylations involving glycosyl bromides to levels matching the efficiency and stereospecificity of glycosyl iodides. Results of our studies will be discussed. | |
| dc.language.iso | en_US | en_US |
| dc.publisher | The University of Arizona. | en_US |
| dc.rights | Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. | en_US |
| dc.subject | Chemistry, Organic. | en_US |
| dc.title | Glycosylations via in situ formation of glycosyl iodides from glycosyl bromides | en_US |
| dc.type | text | en_US |
| dc.type | Thesis-Reproduction (electronic) | en_US |
| thesis.degree.grantor | University of Arizona | en_US |
| thesis.degree.level | masters | en_US |
| dc.identifier.proquest | 1405050 | en_US |
| thesis.degree.discipline | Graduate College | en_US |
| thesis.degree.discipline | Chemistry | en_US |
| thesis.degree.name | M.S. | en_US |
| dc.identifier.bibrecord | .b41939104 | en_US |
| refterms.dateFOA | 2018-08-15T21:48:39Z | |
| html.description.abstract | Glycosyl iodides have proven to be highly efficient and stereospecific glycosyl donors. Unfortunately with such high reactivity, they possess short shelf lives. Glycosyl bromides, on the other hand, are more robust than their iodo-counterparts. But, glycosylations using glycosyl bromides in the absence of Lewis acid catalysts are slow. Recently, we have demonstrated conditions augmenting glycosylations involving glycosyl bromides to levels matching the efficiency and stereospecificity of glycosyl iodides. Results of our studies will be discussed. |
