Dysphagia in Encephalopathic Neonates Treated with Hypothermia

Collins, Michael

dc.contributor.author	Collins, Michael
dc.date.accessioned	2013-04-12T21:47:59Z
dc.date.available	2013-04-12T21:47:59Z
dc.date.issued	2013-03
dc.identifier.uri	http://hdl.handle.net/10150/281173
dc.description	A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.	en
dc.description.abstract	Objective: The purpose of this study is to determine the rate of dysphagia in neonates treated with targeted body temperature reduction as compared to neonates who have not been exposed to hypothermia. Methods: We performed a retrospective study of encephalopathic neonates who were treated with hypothermia and who underwent a modified barium swallow (MBS). For comparison, a group of neonates who had been evaluated with MBS but did not receive hypothermic therapy was identified. This group consisted of non-encephalopathic patients. MBS results were qualified as either normal or abnormal. Results: There was no statistically significant difference in the percentage of abnormal MBS results between the hypothermic and control groups (Fisher’s exact; P = 0.78). The odds ratio for abnormal MBS results in the hypothermia group relative to the control group was 1.2, with 95% confidence interval of 0.42 to 3.8. Significance: These data indicate that hypothermia does not seem to increase short term risk of dysphagia compared to the control group. There is no apparent association between hypothermia and dysphagia. This supports previous findings that hypothermia is a safe treatment for neural injuries in NICU patients.
dc.language.iso	en_US	en
dc.publisher	The University of Arizona.	en_US
dc.rights	Copyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.	en_US
dc.subject.mesh	Gastrointestinal Diseases	en
dc.subject.mesh	Infant, Newborn, Diseases	en
dc.title	Dysphagia in Encephalopathic Neonates Treated with Hypothermia	en_US
dc.type	text; Electronic Thesis	en
dc.contributor.department	The University of Arizona College of Medicine - Phoenix	en
dc.description.collectioninformation	This item is part of the College of Medicine - Phoenix Scholarly Projects 2013 collection. For more information, contact the Phoenix Biomedical Campus Library at pbc-library@email.arizona.edu.	en_US
dc.contributor.mentor	Miller, Jeffrey	en
refterms.dateFOA	2018-09-12T12:08:19Z
html.description.abstract	Objective: The purpose of this study is to determine the rate of dysphagia in neonates treated with targeted body temperature reduction as compared to neonates who have not been exposed to hypothermia. Methods: We performed a retrospective study of encephalopathic neonates who were treated with hypothermia and who underwent a modified barium swallow (MBS). For comparison, a group of neonates who had been evaluated with MBS but did not receive hypothermic therapy was identified. This group consisted of non-encephalopathic patients. MBS results were qualified as either normal or abnormal. Results: There was no statistically significant difference in the percentage of abnormal MBS results between the hypothermic and control groups (Fisher’s exact; P = 0.78). The odds ratio for abnormal MBS results in the hypothermia group relative to the control group was 1.2, with 95% confidence interval of 0.42 to 3.8. Significance: These data indicate that hypothermia does not seem to increase short term risk of dysphagia compared to the control group. There is no apparent association between hypothermia and dysphagia. This supports previous findings that hypothermia is a safe treatment for neural injuries in NICU patients.