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dc.contributor.advisorJeter, Wayburn S.en_US
dc.contributor.authorSoli, Teri Cullen
dc.creatorSoli, Teri Cullenen_US
dc.date.accessioned2013-04-18T09:38:33Z
dc.date.available2013-04-18T09:38:33Z
dc.date.issued1980en_US
dc.identifier.urihttp://hdl.handle.net/10150/282271
dc.description.abstractDialyzable leucocytic extracts (Transfer Factor) were prepared from guinea pigs, rabbits, dogs and cattle sensitized to tuberculin, from cattle and dogs reactive to coccidioidin and from cattle sensitized to 2,4 dinitrochlorobenzene and Pasteurella multocida. These Transfer Factor (TF) preparations were used in intra- and interspecies transfers of delayed hypersensitivity (DH) and cellular immunity (CMI) in guinea pigs, rabbits, dogs, cattle and humans. Various doses and routes of administration were employed. Success of transfer was based upon dermal skin reactivity and/or clinical improvement. Our results suggest the following: (a) interspecies transfer of DH is effective with a variety of species, (b) oral administration of TF is effective and (c) cattle are effective donors of TF for use in humans and other animals because of potential quantity and strong potency of transfer material.
dc.language.isoen_USen_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.subjectDelayed hypersensitivity.en_US
dc.subjectTransfer factor (Immunology)en_US
dc.subjectImmunospecificity.en_US
dc.titleINTERSPECIES TRANSFER OF DELAYED HYPERSENSITIVITY WITH TRANSFER FACTORen_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.identifier.oclc8633089en_US
thesis.degree.grantorUniversity of Arizonaen_US
thesis.degree.leveldoctoralen_US
dc.identifier.proquest8017808en_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineMicrobiology and Medical Technologyen_US
thesis.degree.namePh.D.en_US
dc.description.noteThis item was digitized from a paper original and/or a microfilm copy. If you need higher-resolution images for any content in this item, please contact us at repository@u.library.arizona.edu.
dc.identifier.bibrecord.b13886113en_US
dc.description.admin-noteOriginal file replaced with corrected file July 2023.
refterms.dateFOA2018-06-15T09:01:42Z
html.description.abstractDialyzable leucocytic extracts (Transfer Factor) were prepared from guinea pigs, rabbits, dogs and cattle sensitized to tuberculin, from cattle and dogs reactive to coccidioidin and from cattle sensitized to 2,4 dinitrochlorobenzene and Pasteurella multocida. These Transfer Factor (TF) preparations were used in intra- and interspecies transfers of delayed hypersensitivity (DH) and cellular immunity (CMI) in guinea pigs, rabbits, dogs, cattle and humans. Various doses and routes of administration were employed. Success of transfer was based upon dermal skin reactivity and/or clinical improvement. Our results suggest the following: (a) interspecies transfer of DH is effective with a variety of species, (b) oral administration of TF is effective and (c) cattle are effective donors of TF for use in humans and other animals because of potential quantity and strong potency of transfer material.


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