• Login
    View Item 
    •   Home
    • UA Graduate and Undergraduate Research
    • UA Theses and Dissertations
    • Dissertations
    • View Item
    •   Home
    • UA Graduate and Undergraduate Research
    • UA Theses and Dissertations
    • Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UA Campus RepositoryCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournal

    My Account

    LoginRegister

    About

    AboutUA Faculty PublicationsUA DissertationsUA Master's ThesesUA Honors ThesesUA PressUA YearbooksUA CatalogsUA Libraries

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    KIDNEY FUNCTION AND POST-RENAL MODIFICATION OF URINE IN DESERT QUAIL

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    azu_td_8025222_sip1_m.pdf
    Size:
    3.169Mb
    Format:
    PDF
    Download
    Author
    Anderson, Gary L. (Gary Lee)
    Issue Date
    1980
    Keywords
    Kidneys.
    Uric acid -- Metabolism.
    Urine -- Analysis.
    Gambel's quail.
    Advisor
    Braun, Eldon J.
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    This work is a quantitative description of the renal excretion and the post-renal modification of ureteral urine from native (unanesthetized, uninfused, and normal hydropenic) desert quail, Lophortyx gambelii. The technique used in this study establishes the glomerular filtration rate (GFR), urine flow rate, and urinary excretion of water, sodium, potassium, and uric acid for desert quail in a relatively undisturbed state and in steady-state balance with regard to intake and output of water, sodium, and potassium. In contrast, conventional methods of determining GFR in birds include the use of anesthesia, cloacal or ureteral canulation, and infusion of fluids to introduce filtration markers (e.g. inulin) and to cause a diuresis (e.g. by using mannitol). In the present study, native desert quail had a urine flow rate of about 40 g/kg.day compared to over 500 g/kg.day for desert quail previously studied using conventional methods. Also in the present study, GFR was about 1.6 ml/kg.min which is about 25% lower than previously reported (2.1 ml/kg.min) for desert quail studied with conventional techniques. Renal absorption of the filtered loads of water, sodium and potassium also was determined in the present study. The fractions of the filtered loads reabsorbed by the renal tubules were: for water 98%, for sodium 99.4%, and for potassium 42%. These findings illustrate that renal reabsorption of these filtered substances is less complete in birds than in mammals where, in man for example, about 99% of the water and 99.8% of the sodium are normally reabsorbed. In addition, this study evaluates the role of the cloaca and lower intestines in changing the composition of the ureteral urine. Ureteral urine is modified in the cloaca and lower intestines of the desert quail before being excreted with the final droppings. This modification results in reabsorption of about 70% of the water and sodium and about 80% of the potassium in the ureteral urine. Thus for the desert quail, post-renal reabsorption of water and sodium from ureteral urine produced by the kidneys increases the total amounts of the filtered loads reabsorbed to 99% for water and 99.7% for sodium, which are nearly the same as seen for man. It is concluded that post-renal reabsorption of water and sodium is an important aspect of fluid and electrolyte balance in native desert quail. About 65% of the uric acid present in the ureteral urine was found to be degraded during its passage into the lower intestines. This is particularly significant because trapping of sodium and potassium occurs within the uric acid precipitates which form in bird urine. It was determined that about 20% of the sodium and 33% of the potassium in the ureteral urine are trapped within uric acid precipitates. Degradation of uric acid may increase the reabsorbable pools of these cations and facilitate their reabsorption by the tissues of the lower intestines. Since the intestinal ceca of birds contain large populations of uric acid-decomposing bacteria, and because other studies have suggested large amounts of water are reabsorbed in the ceca of birds, the role of the ceca in post-renal modification of urine was evaluated. The results are not conclusive. Cecaectomized (Cx) birds showed only a transitory increase in water loss when compared to sham operated (Sh) birds. No difference in uric acid excretion was seen between Cx or Sh birds. Thus, no obligatory role for the ceca in post-renal reabsorption of water and electrolytes, or in degradation of uric acid, was evident.
    Type
    text
    Dissertation-Reproduction (electronic)
    Degree Name
    Ph.D.
    Degree Level
    doctoral
    Degree Program
    Graduate College
    Physiology
    Degree Grantor
    University of Arizona
    Collections
    Dissertations

    entitlement

     
    The University of Arizona Libraries | 1510 E. University Blvd. | Tucson, AZ 85721-0055
    Tel 520-621-6442 | repository@u.library.arizona.edu
    DSpace software copyright © 2002-2017  DuraSpace
    Quick Guide | Contact Us | Send Feedback
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.