Utilization of a scientifically operated charge-coupled device detector for high-performance thin-layer chromatographic analysis

Abstract

A high-performance thin-layer chromatographic (HPTLC) separation system coupled with a scientifically operated charge-couple device detector (CCD) has been developed to improve the identification and quantitative analysis of pharmaceutical products and natural toxins. The combination of the fast, easy and high throughput properties of TLC, high speed, sensitivity, wide dynamic range of the CCD detector, and the high reproducibility and accuracy of the micro-nebulization sampler can be used to facilitate pharmaceutical industrial quality control and food industrial safety control. The application of this system in these areas has shown significant improvement in sensitivity, precision, and accuracy.