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    Occupational exposure to azinphos-methyl: Correlating biological markers to environmental residue levels

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    Author
    Gonzales, Melissa
    Issue Date
    1992
    Keywords
    Health Sciences, Occupational Health and Safety.
    Health Sciences, Toxicology.
    Environmental Sciences.
    Advisor
    Crutchfield, Clifton D.
    
    Metadata
    Show full item record
    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    Peach harvester exposure to azinphos-methyl (AZM) residues estimated by the Transfer Factor (TF) ratio of Dislodgeable Foliar Residue (DFR) to Daily Dermal Exposure (DDE) was compared to estimates based on the relationship between dermal exposure and dialkylphosphate metabolite excretion. DFR was monitored in four orchards from the time of pesticide application through harvest. Eleven male harvesters wore cotton tee-shirt dosimeters and provided area-specific skin washes and wipes for DDE monitoring during work operations. Urinary dialkylphosphate metabolites of AZM were also monitored and compared to DDE results. During a later harvest for which DDE was not determined, the dermal exposure estimated by the TF (1,310 μg) was comparable to the estimates based on dialkylphosphate excretion (1,456-1,534 μg). A repeated measures ANOVA showed that harvesters' cholinesterase levels were significantly lower than 'non-harvesters'. No significant reductions in cholinesterase levels were detected over time.
    Type
    text
    Thesis-Reproduction (electronic)
    Degree Name
    M.S.
    Degree Level
    masters
    Degree Program
    Graduate College
    Pharmacology & Toxicology
    Degree Grantor
    University of Arizona
    Collections
    Master's Theses

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