Occupational exposure to azinphos-methyl: Correlating biological markers to environmental residue levels
KeywordsHealth Sciences, Occupational Health and Safety.
Health Sciences, Toxicology.
AdvisorCrutchfield, Clifton D.
MetadataShow full item record
PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
AbstractPeach harvester exposure to azinphos-methyl (AZM) residues estimated by the Transfer Factor (TF) ratio of Dislodgeable Foliar Residue (DFR) to Daily Dermal Exposure (DDE) was compared to estimates based on the relationship between dermal exposure and dialkylphosphate metabolite excretion. DFR was monitored in four orchards from the time of pesticide application through harvest. Eleven male harvesters wore cotton tee-shirt dosimeters and provided area-specific skin washes and wipes for DDE monitoring during work operations. Urinary dialkylphosphate metabolites of AZM were also monitored and compared to DDE results. During a later harvest for which DDE was not determined, the dermal exposure estimated by the TF (1,310 μg) was comparable to the estimates based on dialkylphosphate excretion (1,456-1,534 μg). A repeated measures ANOVA showed that harvesters' cholinesterase levels were significantly lower than 'non-harvesters'. No significant reductions in cholinesterase levels were detected over time.
Degree ProgramGraduate College
Pharmacology & Toxicology