1. Mechanistic studies on the formation of glycosyl iodides 2. Synthesis of amino sugars via glycosyl iodides
AuthorNguyen, Truc Ngoc, 1972-
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PublisherThe University of Arizona.
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AbstractThe synthesis of oligosaccharides remains a challenging task. In our studies, we applied glycosyl iodides to the synthesis of oligosaccharides. The mechanism of formation of glycosyl iodides from anomeric acetates of glucose, galactose and mannose, and 1,2 and 1,6 anhydro sugars were investigated by NMR. Glycosyl iodides were then applied in glycosidation studies and specifically in the synthesis of a precursor to the trisaccharide of Lewis x, a blood group antigen.
Degree ProgramGraduate College