1. Mechanistic studies on the formation of glycosyl iodides 2. Synthesis of amino sugars via glycosyl iodides
Issue Date
1998Keywords
Chemistry, Organic.Advisor
Gervay, JacquelynMetadata
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The University of Arizona.Rights
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.Abstract
The synthesis of oligosaccharides remains a challenging task. In our studies, we applied glycosyl iodides to the synthesis of oligosaccharides. The mechanism of formation of glycosyl iodides from anomeric acetates of glucose, galactose and mannose, and 1,2 and 1,6 anhydro sugars were investigated by NMR. Glycosyl iodides were then applied in glycosidation studies and specifically in the synthesis of a precursor to the trisaccharide of Lewis x, a blood group antigen.Type
textThesis-Reproduction (electronic)
Degree Name
M.S.Degree Level
mastersDegree Program
Graduate CollegeChemistry