Medication Regimes and Dosing in Fibromyalgia with and without Co-Morbid Depression
AdvisorRoss, Rebecca L.
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PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
AbstractThe purpose of this secondary analysis was to determine whether or not prescribers are adequately treating depression in those with fibromyalgia (FM). Aim 1 was to determine whether therapeutic dosages of antidepressant medications more closely correlated with FM severity or depression severity, using Pearson’s r correlation coefficients. Aim 2 was to determine if there were differences in antidepressant medication classes between those with melancholic (MDE) versus atypical (ADE) depressive episodes using the Chi-squared test. Aim 1 measured FM severity via the Fibromyalgia Impact Questionnaire (FIQ) total score and MDD severity via the Structured Interview Guide for the Hamilton Depression Rating Scale with Atypical Depression Supplement (SIGH-ADS) total score (FIQ: r = -0.883-.210, p =.132-.923; SIGH-ADS: -0.178 to 0.133; 0.326 to 0.886). The Chi-squared test found no difference in the antidepressant medication classes taken by those with MDE versus those with ADE: Χ²(2, n=57)= 1.34, p=0.51. As the providers with the most contact time with patients, nurses are uniquely positioned to identify undertreated MDD in those with FM and advocate for adequate treatment.
Degree ProgramHonors College