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dc.contributor.authorSpillane, Kaitlyn Ann
dc.creatorSpillane, Kaitlyn Annen
dc.date.accessioned2015-05-22T22:45:57Zen
dc.date.available2015-05-22T22:45:57Zen
dc.date.issued2014en
dc.identifier.urihttp://hdl.handle.net/10150/555550en
dc.description.abstractOsteoporosis and obesity are major public health concerns with a combined cost of $164 billion spent in the United States alone. The effect of adipose tissue on bone was thought to be protective however further research suggests there is a detrimental effect through a connection involving the endocrine system. Insulin, adiponectin and leptin all affect the skeletal system and adipose tissue. Excess adipose tissue in individuals correlates with hyperinsulinemia, high levels of leptin and low levels of adiponectin. The connection between adipose tissue and bone is especially important in children during the pubertal growth spurt. During this time strong bones are developed in children that will carry them throughout their life. If adipose tissue has a negative effect on bone development bone strength may be impaired resulting in higher risk for fractures later in life. This review presents research in the areas of obesity and osteoporosis with the aim of identifying interrelationships, specifically focusing on children and bone development, and whether obesity has positive or negative effects on bone.
dc.language.isoen_USen
dc.publisherThe University of Arizona.en
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en
dc.titleDoes Excess Body Fat Impair Bone Development?en_US
dc.typetexten
dc.typeElectronic Thesisen
thesis.degree.grantorUniversity of Arizonaen
thesis.degree.levelbachelorsen
thesis.degree.disciplineHonors Collegeen
thesis.degree.disciplinePhysiologyen
thesis.degree.nameB.S.H.S.en
refterms.dateFOA2018-09-08T11:05:44Z
html.description.abstractOsteoporosis and obesity are major public health concerns with a combined cost of $164 billion spent in the United States alone. The effect of adipose tissue on bone was thought to be protective however further research suggests there is a detrimental effect through a connection involving the endocrine system. Insulin, adiponectin and leptin all affect the skeletal system and adipose tissue. Excess adipose tissue in individuals correlates with hyperinsulinemia, high levels of leptin and low levels of adiponectin. The connection between adipose tissue and bone is especially important in children during the pubertal growth spurt. During this time strong bones are developed in children that will carry them throughout their life. If adipose tissue has a negative effect on bone development bone strength may be impaired resulting in higher risk for fractures later in life. This review presents research in the areas of obesity and osteoporosis with the aim of identifying interrelationships, specifically focusing on children and bone development, and whether obesity has positive or negative effects on bone.


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