• Refractory Insomnia in an Adolescent with Total Blindness

      Tubbs, Andrew S; Grandner, Michael A; Combs, Daniel; Univ Arizona, Dept Psychiat, Sleep & Hlth Res Program; Univ Arizona, Dept Pediat; Univ Arizona, Dept Med (YALE J BIOLOGY MEDICINE, INC, 2019-06-27)
      We present a totally blind adolescent with refractory insomnia due to a combination of Non-24 hour sleep-wake disorder and restless leg syndrome that was successfully treated with tasimelteon, iron replacement, and gabapentin. To our knowledge, this is the first published report of treatment of N24 with tasimelteon in an adolescent. In addition, this case highlights the importance of recognizing and treating multifactorial causes of insomnia.