Now showing items 35491-35510 of 39117


      Rydgren, A. E. (Alfred Eric), 1945- (The University of Arizona., 1975)
    • T-cell Receptor Vβ8.1 Peptide Reduces Coxsackievirus-induced Cardiopathology During Murine Acquired Immunodeficiency Syndrome and Aging.

      Sepulveda, Ramon Tomas; Marchalonis, John J.; Payne, Claire; Ahmad, Nafees; Bernstein, Harris; Watson, Ronald R. (The University of Arizona., 2005)
      Infection of people with human immunodeficiency virus (HIV) as well as LPBM5 infection in mice results in progressive deterioration of the immune system in the majority of untreated hosts. Peptide immunotherapy has been shown to be effective in the stimulation or immunoregulation of T-helper 1 (TH1) and T-helper 2 (TH2) response subsets. In murine acquired immunodeficiency syndrome (AIDS), TH1 deficiency enables the host to be susceptible to coxsackievirus infection, inducing cardiopathology in a short period. T-cell receptor (TCR) Vβ8.1 peptide, a 16-mer peptide containing the entire CFR1 segment and part of the FR2 region of human Vβ8, showed both an immunoregulating and immunostimulating effect in murine AIDS. TCR Vβ8.1 peptide acts on T cells promoting interleukin-2 production and therefore enhancing a cellmediated immune response. It retarded development of cardiopathology due to coxsackievirus infection. Retrovirus infected mice treated with the peptide showed a longer life span than the nontreated retrovirus infected animals.
    • T. E. Brown as revealed in his letters and poems

      Felmley, Mildred H. (The University of Arizona., 1931)
    • T. H. Huxley's defense of Charles Darwin's Origin of species

      Harvey, Mary Jolyne, 1934- (The University of Arizona., 1960)
    • T. S. Eliot's civilized savage: Religious eroticism and poetics

      Schneidau, Herbert; MacDiarmid, Laurie J., 1964- (The University of Arizona., 1997)
      Current studies of T. S. Eliot explore his social poetic, his religion, his sexuality, and his place in the history of modernism and contemporary poetics. "T. S. Eliot's Civilized Savage" links these interests, beginning with Eliot's controversial masculinity. Eliot constructs an impotent poet who engages in celibate heterosexual relationships; he uses comparative religious studies (such as Frazer's Golden Bough and Harrison's Themis) to transform these relationships into a social imperative. "The Death of Saint Narcissus," "The Love Song of J. Alfred Prufrock" and "Hysteria" compare Eliot's poet to Frazer's self-sacrificing god, pitting him against a voracious mother goddess who demands the poet's self-sacrifice. Eliot's lady poses as an alibi for his own hysteria and as a spiritual catalyst; the poet is reborn in the Father. By Ash Wednesday, Eliot rewrites heterosexuality using Christian iconography. "Tradition and the Individual Talent" exposes Eliot's ambivalent relationship to masculinity and maternity: though Eliot describes a purely scientific poetic reproduction, the essay bears traces of his maternal fascinations, though these images are sterilized by the rhetoric of Immaculate Conception. By 1927, Eliot converts to the Church of England, abandons Vivienne, rekindles a chaste romance with Emily Hale, develops his poetry of confession, and refashions the Lady. Now she acts as the perfect vessel for God's Word, and her "torn and most whole" body eliminates the threat of sexual intercourse. Subsumed in her, Eliot's poet becomes God's womb. Eliot's contemporary fall from grace seems to stem from repeated exposures of his erotic and religious masquerades. Christopher Ricks's publication of Eliot's notebooks foregrounds Eliot's racist, sexist and classicist ideology and Michael Hastings's Tom and Viv suggests that Eliot blamed his hysteria on Vivienne while profiting from the marriage. Eliot's mysticism appears to be an impotent attempt to escape domestic horrors, but a re-examination of this diagnosis may reveal our own construction of sexuality, poetics, politics and spirituality. As we recoil from Eliot's corrosive "conservatism" perhaps we safeguard our own.
    • Tabasco wilt: nature of host-virus interaction

      Zouba, Ali (The University of Arizona., 1977)
    • The Tachinid flies of Arizona

      Simpson, Roy William, 1931- (The University of Arizona., 1957)
    • THE TACOMA FLATS A study of post-industrial urban waterfront rejuvenation

      Herman, Brandon (The University of Arizona., 2014)
      Named after nearby Mount Rainier, Tacoma has been on a slow but steady rebound from the economic decline of a postindustrial nation. Founded at the terminus of the Northern Pacific Railroad in 1873, Tacoma’s economy was historically based largely on the exportation of natural resources, such as timber and coal. Although still trying to find its stride, this Pacific Northwest city has retained, for the most part, the blue collar industrial grit that the city was originally founded on. Like most industrial cities, Tacoma suffered a prolonged decline in the mid-20th century. An effect of suburbanization and disinvestment, the city still finds many of its historic structures and vacant parcels largely underutilized. However, since the 1990’s, the city has felt some effects of reinvestment. The University of Washington integrated a Tacoma campus into the Downtown core, Tacoma Link, the state’s first light rail line, and the Thea Foss Waterway urban waterfront redevelopment all helped to provide the local economy with a much needed boost. Additional investments in the downtown include the restoration of Union Station and the creation of the Museum District, which includes The Museum of Glass, Bridge of Glass, Tacoma Art Museum, Washington State History Museum, Lemay-America’s Car Museum, Children’s Museum of Tacoma, and Foss Waterway Seaport - a centuryold shipping warehouse and maritime heritage educational center. Tacoma also posses a thriving theatre district. Perhaps we have disinvestment to thank for the lack of redevelopment that has ultimately lead to the preservation of vast blocks of historic Tacoma. This fact, along with a more affordable housing market, and greater investment interest help lay the foundation for a future as a complete and healthy metropolitan center. This city inherently holds many of the desirable amenities, spatial arrangements, and historical vernacular that other cities around the country are trying to recreate post urban renewal era. The Tacoma Flats programming and design makes many assumptions regarding the future of this city - a fully realized economy, a large regional population expansion, and increased efficiencies in port functions. This 2050 vision is just that, a glimpse of how underutilized former industrial areas adjacent to the downtown core could be used to accommodate the growth, health, and ecological function of this historically rich region of the Puget Sound. The Tacoma Flats 2050 vision is simply the realization of possibilities.
    • The tactic and floral constancy of foraging bumblebees: pure legitimate foragers, pure nectar-robbers, and mixed tactic individuals visiting one or more host species

      Bronstein, Judith L.; Wang, Karen (The University of Arizona., 2017-12)
      Floral visitors in a Colorado bumblebee community engage in two main foraging tactics: nectar-robbing and legitimate foraging. An individual may employ one tactic consistently throughout a foraging bout or switch and may visit one consant host species or multiple. In order to understand foraging strategies, tactic and floral constancy must jointly be investigated with pollen and nectar foraging. I do so in this second ever study to compare floral visit observations with pollen load compositions. I found that nectar-robbers carried pollen less or as often as legitimate foragers, depending on robber and host species. This suggests that pollen-carrying robbers are mixed tactic individuals that could, in one foraging bout, cheat and cooperate with its plant partner. Visitors were observed switching tactic within a host species and switching tactic between host species. Both robbers and legitimate foragers carried pollen from the same host species they visited for nectar when that host species could be both robbed for nectar and legitimately foraged for pollen. These results suggest that tactic switching is more common than previously thought and that floral constancy is frequently maintained across tactic switches, unless host floral morphology constrains behavior and forces a host switch.
    • A tactical analysis of the Sino-Soviet dispute

      Hayes, Louis D. (The University of Arizona., 1964)
    • Tactical Light Device

      Ellis, Jonathan D.; Esham, Nathan Dean; Koshel, John; Schwiegerling, Jim (The University of Arizona., 2019)
      Less-than-lethal tools are an important selection of equipment for law enforcement officers as it reduces the risk of physical intervention for both the user and the target. While these tools are labeled as less-than-lethal, this classification does not mean that the equipment lacks the ability to cause injury. One such piece of equipment in this category is known as a flashbang. This equipment is explosive-based and as such, comes with the risks that are associated with handling and using explosives. The aim of this thesis is to produce a product that could serve as an alternative to flashbang devices that is based on LEDs rather than explosives. Two prototype devices were manufactured for this thesis for this purpose. The first prototype served as a proof of concept that high-power LEDs could be used to fulfil the requirements set. As a proof of concept, the design of the device was intended to be simple, so the shape of a cube was utilized. Several ideas for the shell of the device were tested with this iteration of the prototype. While the individual parts of the design were simple, assembly of the device proved to be overly difficult and reduced usable interior space. For the second prototype, a greater emphasis was placed on the device of the frame to maximize the manufacturability and functionality. These changes led to a design that was sturdier and easier to assembly than the first prototype. The number of LEDs was greatly increased as well to maximize the visual effect of the device. The second prototype achieved all goals set for the this and serves as a nearly ready example for further testing to before being production ready.

      Thornton, Susan Ruth. (The University of Arizona., 1984)

      McRae, Lorin Pose, 1936- (The University of Arizona., 1968)
    • Taft and Mexico: neutrality, intervention and recognition, 1910-1913

      Farrier, Paul Everest, 1934- (The University of Arizona., 1966)

      Gray, Frederic Charles, 1918- (The University of Arizona., 1970)
    • Tai Chi for Driving Health: Cognitive and Physical Function Related to Safe Driving Performance among Older Tai Chi Practitioners

      Taylor-Piliae, Ruth E.; Miller, Sally May; Taylor-Piliae, Ruth E.; Taylor-Piliae, Ruth E.; Insel, Kathleen C.; Reed, Pamela G. (The University of Arizona., 2015)
      By the year 2030 it is estimated that one in five licensed drivers in the United States will be over the age of 65. Driving allows engagement in the community for shopping, banking, maintaining social connections, and accessing health care. However, age-related decline can impact many of the cognitive processes and physical abilities necessary for safe driving performance. Exercise has beneficial effects on specific cognitive processes and physical function, many of which are related to safe driving performance. Tai Chi exercise is known to benefit cognitive and physical function and may influence safe driving performance. The aims of this observational study were to: 1) examine relationships between Tai Chi exercise habits, cognitive processes and physical function related to safe driving performance, 2) compare cognitive processes and physical function related to safe driving performance to normative reference values, and 3) explore potential predictors of safe driving performance. Fifty-eight current Tai Chi practitioners (mean age = 72.9), with a median of greater than three years of Tai Chi practice were recruited from community Tai Chi classes and Tai Chi events. Participants completed a study packet describing self-reported Tai Chi and non-Tai Chi exercise habits, driving habits, self-report measures of dispositional mindfulness (Mindful Attention Awareness Scale, MAAS) and overall well-being (Vitality Plus Scale, VPS), personal history, and health history. Investigator-administered study measures included the DrivingHealth InventoryTM, digit span tests, the Driving Scenes Test, and the Right Foot Tapping test. Statistically significant correlations were found between several study measures. Compared to normative reference values participants performed better on several cognitive and physical measures, and on the MAAS and the VPS measures. Small to large effect sizes were calculated. The strongest predictor of safe driving performance was the digit span backward. Tai Chi exercise has the potential to positively impact cognitive processes and physical function related to safe driving performance through aerobic exercise mechanisms, development of mindfulness, and beneficial influence on overall vitality. The results of this study support the need for further investigation of Tai Chi exercise as a strategy to maintain safe driving performance in older adults.
    • Tailings pond seepage and sulfate equilibrium in the Pima mining district, Pima County, Arizona

      Bassett, R. L.; Artiola, J. F.; Scovill, Georgia Lynn, 1962- (The University of Arizona., 1988)
      Mining activity is suspected of contributing sulfate and total dissolved solids (TDS) to ground water downgradient of the Pima mining district. High ionic concentrations in tailing impoundments suggest that tailings-pond recharge may be a source of the contamination. Experiments indicated that sulfate is not significantly produced by inorganic sulfide oxidation in the tailings ponds. Tailings pond water chemistries were compared with historical water quality analyses in the Pima district. The U.S.G.S. computer program PHREEQE modeled saturation indices for anhydrite, calcite, fluorite, and gypsum in water chemistries throughout the study area. Well water downgradient of the mines had lower saturation indices than tailings pond water which discredits the claim that tailings-pond recharge is acquiring salts as it percolates to the aquifer. Evidence supports the opinion that tailings pond seepage is contributing to the sulfate and TDS content in ground water downgradient of the ponds.
    • Tailings Storage Facility (TSF) Stability and Water Management

      Kim, Kwangmin; Jeong, Yongsik; Kemeny, John M.; Tenorio, Victor Octavio; Son, Young-Jun (The University of Arizona., 2020)
      Tailings storage facilities (TSFs) are among the largest geotechnical structures in the world and operate for adequate and safe storage of tailings during and after mining activities. Ensuring the stability of these enormous structures has been a long-standing environmental liability for mining-related communities; the failures of TSFs can not only undermines the sustainable development of a mine, but also can cause irreparable hazards and damage to those communities and environments. This document presents research regarding three main topics related to TSFs water management. The first topic is development of site-specific guidelines for safe TSF water management. In this regard, the study focuses on determining the optimal beach distance from the decant pond to the crest, which can be a practical and easy monitoring criterion for securing TSF stability. 2D stress-seepage coupled analyses were conducted to evaluate geotechnical stability; additionally, water increments that increase due to unexpected weather conditions (heavy rainfall and strong wind) were considered for the optimal beach distance. The results of this research can be useful in developing a TSF risk level guideline of the testing site. The second topic is investigation of the potential of an environmentally-friendly polymer as a new drag reduction agent (DRA) to reduce frictional pressure loss and also to conserve water. Lab-scale pipe loop tests examined the effect of the polymer on the pressure loss of the tailings slurry in pipe flows. The experiment results confirmed the potential for using the polymer as a new DRA. Findings showed that pressure loss decreased with increasing polymer percentages up to 4%, but increased above concentrations of 4%. 3D numerical models of computational fluid dynamics (CFD) simulations were developed and validated based on the pipe loop test results. The model provided the potential amount of water and transportation energy saving with minimal changes of pressure loss, induced by solid concentration increases. The final topic deals with usage of the new DRA. When the DRA is employed and solids concentration is increased, the study explored the relevant operating issues, such as settling of tailings particles in pipelines, and accelerating pipeline wear using 3D CFD numerical simulations. The polymer used in the second study reported here was expected to improve the efficiency of tailings slurry flows in pipelines. The results confirmed that by employing the new DRA, the minimal changes of pressure loss levels could be achieved even though there were increases in solids concentration. The polymer also increased the flow velocity, making it possible to transport tailings faster than the critical velocity at which the particle settlement begins. Also, the addition of the polymer resulted in an increase of the erosion rate, due to increased flow velocity, but the total amount of erosion was reduced at certain solids concentrations.