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Inaccuracies in the Second Season of the Medical Drama, House, MDApgar, David; Ball, Nicole; Nguyen, Tracy; Walenga, Annie; College of Pharmacy, The University of Arizona (The University of Arizona., 2009)OBJECTIVES: The purpose of this work was to quantify the magnitude of factual inaccuracies in the first twelve episodes of the second season of the medical drama, House, MD. METHODS: This study was a descriptive retrospective evaluation of the first twelve episodes in the second season of the popular television show, House, MD. The degree of accuracy of the signs and symptoms (presentation), diagnosis, and treatment for the one major disease portrayed in each show was rated on a scale of one to four. Each researcher evaluated these ratings independently, and after subsequent collaborative discussion, a combined rating was determined for all the data. RESULTS: Both a three-way ANOVA and Kruskal-Wallis data analyses found significance among the data. The Tukey HSD post hoc test revealed a significant difference between the accuracy of signs and symptoms to treatment variables (p = 0.045). Analysis by the Mann-Whitney U test also determined that a significant difference was evident between the accuracy of signs and symptoms when compared with treatment (p = 0.022). CONCLUSIONS: The treatments presented in the twelve episodes evaluated were determined to be more accurate than the show's description of the patient's presenting signs and symptoms.