• A Single Center, Retrospective Chart Review Studying Survival Rates in Patients Treated with IMiDs for Multiple Myeloma

      McBride, Ali; Chung, Jisu; Patel, Toral; Trinh, Christina; College of Pharmacy, The University of Arizona (The University of Arizona., 2018)
      Specific Aims: To evaluate the survival rate between dose adjustment group and non-dose adjustment group in patients diagnosed with multiple myeloma taking IMids. Methods: In this retrospective study design, a total of 100 patients diagnosed with multiple myeloma who received at least one dose of studied IMids were included. The primary finding was survival rate between the dose adjustment group and the non-adjustment group. The secondary findings include the prevalence of side effects and the length of survival. Chi square test was used to analyze the data collected. Main Results: Of the 100 patient charts reviewed, 37 subjects (37%) were dose adjusted (dose adjustment group) whereas 63 subjects (63%) didn’t require dose adjustment (non-dose adjustment group). The incidence of death in both groups were not statistically different with 4 death in dose adjustment group and 7 deaths in non-adjustment group (p=0.96). The most commonly reported side effects in both groups were bone marrow suppression (24.8%), anemia (15.3%), fatigue (14.6%), and diarrhea (12.4%). Conclusions: The incidence of death in both dose adjusted group and non-dose adjusted group were not statistically different (p=0.96).