USE OF IMPLANTED TELEMETRY IN VASCULAR RESEARCH

Abstract

This paper outlines a program to study the development and progression of essential hypertension in dogs through the use of totally implanted telemetry. In light of the role that social interaction may play in the development of hypertension in man, emphasis is placed on inducing and monitoring the effects of social strain in the dog: and because of the role the kidney may play in the development of hypertension, a model for renal flow has been developed. The effect that pharmacological concentrations of vasodilator and vasoconstrictor agents have on renal hemodynamics are evaluated. Preliminary data from investigations on the renal hemodynamics of unrestrained dogs in various stages of psychophysiological stress are presented.