• Login
    View Item 
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UA Campus RepositoryCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournal

    My Account

    LoginRegister

    About

    AboutUA Faculty PublicationsUA DissertationsUA Master's ThesesUA Honors ThesesUA PressUA YearbooksUA CatalogsUA Libraries

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    1756-8722-6-22.pdf
    Size:
    272.3Kb
    Format:
    PDF
    Download
    Author
    Wang, Yiying
    Wang, Yue
    Li, Jie
    Cragun, Janiel
    Hatch, Kenneth
    Chambers, Setsuko
    Zheng, Wenxin
    Affiliation
    Department of Obstetrics and Gynecology, Henan Province People’s Hospital Zhengzhou, Henan, China
    Department of Obstetrics and Gynecology, University of Arizona, Tucson, AZ, USA
    Department of Pathology, University of Arizona College of Medicine, Tucson, AZ, USA
    Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Shandong, China
    Arizona Cancer Center, University of Arizona, Tucson, AZ, USA
    Issue Date
    2013
    
    Metadata
    Show full item record
    Publisher
    BioMed Central
    Citation
    Wang et al. Journal of Hematology & Oncology 2013, 6:22 http://www.jhoonline.org/content/6/1/22
    Journal
    Journal of Hematology & Oncology
    Rights
    © 2013 Wang et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
    Collection Information
    This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
    Abstract
    Lynch syndrome (LS), an autosomal dominant inherited cancer susceptibility syndrome, also known as hereditary non-polyposis colon cancer (HNPCC), is caused by a germline mutation in one of several DNA mismatch repair (MMR) genes. LS is the most common presentation of hereditary colorectal cancer (CRC), accounting for about 2-5% of all CRC cases. More recently, it is found that a similar number of endometrial cancers is also due to one of the MMR gene mutations. There has been significant progress in LS-related CRC in terms of molecular pathogenesis, risks, genetic basis, and cancer prevention. In contrast, the advance about LS-related endometrial cancer (EC) is very much limited. In this commentary, we summarize the main clinicopathologic features of LS-related EC and propose universal screening for LS in individuals with endometrial cancer.
    EISSN
    1756-8722
    DOI
    10.1186/1756-8722-6-22
    Version
    Final published version
    Additional Links
    http://www.jhoonline.org/content/6/1/22
    ae974a485f413a2113503eed53cd6c53
    10.1186/1756-8722-6-22
    Scopus Count
    Collections
    UA Faculty Publications

    entitlement

     
    The University of Arizona Libraries | 1510 E. University Blvd. | Tucson, AZ 85721-0055
    Tel 520-621-6442 | repository@u.library.arizona.edu
    DSpace software copyright © 2002-2017  DuraSpace
    Quick Guide | Contact Us | Send Feedback
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.