Effectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck cancer
Affiliation
Department of Radiation Oncology, University of Arizona, Tucson, AZ, USADepartment of Radiation Oncology, University of Bern, Bern, Switzerland, NC, USA
Department of Radiation Oncology, University Hospitals of Geneva, Switzerland, Geneva, USA
University of Galveston Medical School, Galveston, TX, USA
San Antonio Cancer Center, San Antonio, TX, USA
Florida Radiation Oncology Group, Palatka, FL, USA
Marshfield Clinic, Marshfield, WI, USA
Radiation Oncology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724-5081, USA
Department of Radiation Oncology, Southwest PET/CT Institute, Tucson, AZ, USA
Issue Date
2012Metadata
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BioMed CentralCitation
Nguyen et al. BMC Cancer 2012, 12:253 http://www.biomedcentral.com/1471-2407/12/253Journal
BMC CancerRights
© 2012 Nguyen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0).Collection Information
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.Abstract
BACKGROUND:The aim of the study is to assess the effectiveness of intensity-modulated radiotherapy (IMRT) or image-guided radiotherapy (IGRT) for the prevention of retropharyngeal nodal recurrences in locally advanced head and neck cancer.METHODS:A retrospective review of 76 patients with head and neck cancer undergoing concurrent chemoradiation or postoperative radiotherapy with IMRT or IGRT who were at risk for retropharyngeal nodal recurrences because of anatomic site (hypopharynx, nasopharynx, oropharynx) and/or the presence of nodal metastases was undertaken.The prevalence of retropharyngeal nodal recurrences was assessed on follow-up positron emission tomography (PET)-CT scans.RESULTS:At a median follow-up of 22months (4-53months), no patient developed retropharyngeal nodal recurrences.CONCLUSION:Prophylactic irradiation of retropharyngeal lymph nodes with IMRT or IGRT provides effective regional control for individuals at risk for recurrence in these nodes.EISSN
1471-2407Version
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http://www.biomedcentral.com/1471-2407/12/253Scopus Count
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Except where otherwise noted, this item's license is described as © 2012 Nguyen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0).