Transcatheter patent foramen ovale closure versus medical therapy for cryptogenic stroke: a meta-analysis of randomized clinical trials
AffiliationDepartment of Internal Medicine, University of Arizona, Tucson, AZ 85714, USA
Department of Cardiovascular Diseases, University of Arizona, 3950 S Country Club Road, Suite 200, Tucson, AZ 85714, USA
Department of Biostatistics, University of Arizona, Tucson, AZ 85714, USA
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CitationRiaz et al. BMC Cardiovascular Disorders 2013, 13:116 http://www.biomedcentral.com/1471-2261/13/116
JournalBMC Cardiovascular Disorders
Rights© 2013 Riaz et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
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Abstractp=0.038).CONCLUSIONS:In this meta-analysis, using intention-to-treat analysis, transcatheter device closure of PFO was not superior to standard medical therapy in the secondary prevention of cryptogenic stroke. Transcatheter closure was superior using per-protocol analysis.
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