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    A Retrospective Evaluation of Eribulin Dosing Schedules in Metastatic Breast Cancer

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    Author
    Gagliardo, Camille
    Lybeck, Megan
    Bowles, Harmony
    Affiliation
    College of Pharmacy, The University of Arizona
    Issue Date
    2016
    Keywords
    Retrospective Evaluation
    Eribulin
    Metastatic
    Breast Cancer
    MeSH Subjects
    Breast Neoplasms
    eribulin
    Drug Therapy
    Advisor
    Bowles, Harmony
    
    Metadata
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    Rights
    Copyright © is held by the author.
    Collection Information
    This item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.
    Publisher
    The University of Arizona.
    Abstract
    Objectives: To determine the number of patients treated with eribulin who required an alternate dosing schedule other than “day 1/day 8” due to side effects. Methods: Chart reviews were conducted on all patients who met inclusion criteria. Data collected included patient demographics, history of surgery/radiation, number of past chemotherapy treatments, and lab values prior to each eribulin cycle. Results: A total of 37 patients met inclusion criteria for this study. Ten patients were initially started on the “day 1/day 8” schedule and 3 of those patients required a change to the extended “day 1/day 15” schedule. The remaining 27 patients were started on the extended schedule. Conclusions: The number of patients requiring a dosing schedule change due to side effects was not statistically significant. This finding was due to the fact that the majority of patients were started on an alternate dosing schedule in the beginning of treatment. More extensive studies would be required to determine if a majority of patients would require this alternate dosing schedule, and if this should be initiated in all patients starting on eribulin.
    Description
    Class of 2016 Abstract
    Collections
    Pharmacy Student Research Projects

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