Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope
AffiliationCollege of Optical Sciences, The University of Arizona
Department of Biomedical Engineering, The University of Arizona
MetadataShow full item record
PublisherPublic Library of Science
CitationExpanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope 2015, 10 (9):e0139396 PLOS ONE
Rights© 2015 Welge, Barton. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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AbstractOptical coherence tomography (OCT) is a useful imaging modality for detecting and monitoring diseases of the gastrointestinal tract and other tubular structures. The non-destructiveness of OCT enables time-serial studies in animal models. While turnkey commercial research OCT systems are plenty, researchers often require custom imaging probes. We describe the integration of a custom endoscope with a commercial swept-source OCT system and generalize this description to any imaging probe and OCT system. A numerical dispersion compensation method is also described. Example images demonstrate that OCT can visualize the mouse colon crypt structure and detect adenoma in vivo.
DescriptionUA Open Access Publishing Fund
VersionFinal published version