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    Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage Diffuse Large B-Cell Lymphoma: Final and Long-Term Analysis of Southwest Oncology Group Study S8736.

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    Name:
    JCO-2016-Stephens-JCO.2015.65. ...
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    Description:
    Final Published Version
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    Author
    Stephens, Deborah M
    Li, Hongli
    LeBlanc, Michael L
    Puvvada, Soham D
    Persky, Daniel
    Friedberg, Jonathan W
    Smith, Sonali M
    Affiliation
    Univ Arizona
    Issue Date
    2016-09-01
    
    Metadata
    Show full item record
    Publisher
    AMER SOC CLINICAL ONCOLOGY
    Citation
    Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage Diffuse Large B-Cell Lymphoma: Final and Long-Term Analysis of Southwest Oncology Group Study S8736. 2016, 34 (25):2997-3004 J. Clin. Oncol.
    Journal
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    Rights
    Copyright © 2016, American Society of Clinical Oncology.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Utility of combined-modality therapy for patients with limited-stage diffuse large B-cell lymphoma (DLBCL) was shown in the Southwest Oncology Group (SWOG) S8736 study, where three cycles of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus radiotherapy (CHOP3RT) improved 5-year progression-free (PFS) and overall survival (OS) compared with eight cycles of CHOP (CHOP8). Subsequent analysis showed an unexpected overlap of the PFS curves. We aimed to confirm and investigate this observation by performing long-term analysis of SWOG S8736 and evaluating these data alongside data from similar patients receiving rituximab and CHOP3RT (SWOG S0014 study).
    Note
    Published online ahead of print at www.jco.org on July 5, 2016. 12 month embargo.
    ISSN
    1527-7755
    PubMed ID
    27382104
    DOI
    10.1200/JCO.2015.65.4582
    Version
    Final published version
    Sponsors
    National Institutes of Health (NIH)/National Cancer Institute (NCI)/National Clinical Trials Network [CA180888, CA180819, CA180801, CA 180834, CA 180846, CA180835, CA180818, CA180830, CA180828]; NIH/NCI Community Oncology Research Program Grants [CA189953, CA189952, CA189954, CA189808, CA189830, CA189957, CA189822, CA189853, CA189860]
    Additional Links
    http://jco.ascopubs.org/content/early/2016/06/30/JCO.2015.65.4582.abstract
    ae974a485f413a2113503eed53cd6c53
    10.1200/JCO.2015.65.4582
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