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dc.contributor.authorWerner, Liliana
dc.contributor.authorStover, John C.
dc.contributor.authorSchwiegerling, Jim
dc.contributor.authorDas, Kamal K.
dc.date.accessioned2016-11-28T18:12:00Z
dc.date.available2016-11-28T18:12:00Z
dc.date.issued2016-06-17
dc.identifier.citationEffects of Intraocular Lens Opacification on Light Scatter, Stray Light, and Overall Optical Quality/Performance 2016, 57 (7):3239 Investigative Opthalmology & Visual Scienceen
dc.identifier.issn1552-5783
dc.identifier.doi10.1167/iovs.16-19514
dc.identifier.urihttp://hdl.handle.net/10150/621421
dc.description.abstractPURPOSE. To evaluate light scatter and stray light in intraocular lenses (IOLs) explanted because of postoperative opacification (13 calcified hydrophilic acrylic, 1 calcified silicone, and 4 polymethylmethacrylate [PMMA] lenses with snowflake degeneration), as well as effect of opacification on other optical quality/performance indicators, in comparison with controls. METHODS. The Complete Angle Scatter Instrument (CASI) scatterometer was used to measure the forward light scattering (FLS) of the IOLs, and the stray light values at various angles were calculated from the measured FLS. Modulation transfer function (MTF) was obtained with an optical bench, and a Badal optometer was used to obtain letter chart images through the lenses. Back light scatter and light transmittance were also measured. RESULTS. Average stray light values (Log (s)) at a scattered angle of 100 were 1.79 +/- 0.37 for hydrophilic acrylic IOLs (controls 0.36 +/- 0.05), 1.53 for the silicone lens (control 0.41), and 1.62 +/- 0.46 for PMMA IOLs (control 0.25). Stray light was significantly higher for explanted opacified lenses (N = 18) in comparison with controls (N = 7; two-tail P < 0.001 at 100). Modulation transfer function and Badal image contrast were drastically reduced in lenses with calcification and snowflake degeneration. CONCLUSIONS. Different studies described the impact of stray light in human vision, with serious hindrance above 1.47 Log (s). Lenses explanted from patients because of clinically significant opacification are associated with a considerable increase in light scatter and stray light, as well as with a decline of other optical quality/performance indicators.
dc.description.sponsorshipResearch to Prevent Blindness, Inc. (New York, NY, USA); Alcon Laboratories (Fort Worth, TX, USA)en
dc.language.isoenen
dc.publisherASSOC RESEARCH VISION OPHTHALMOLOGY INCen
dc.relation.urlhttp://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.16-19514en
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.en
dc.subjectintraocular lensen
dc.subjectstraylighten
dc.subjectforward light scatteringen
dc.titleEffects of Intraocular Lens Opacification on Light Scatter, Stray Light, and Overall Optical Quality/Performanceen
dc.typeArticleen
dc.contributor.departmentUniv Arizona, Coll Opt Scien
dc.identifier.journalInvestigative Opthalmology & Visual Scienceen
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
dc.contributor.institutionJohn A. Moran Eye Center University of Utah, Salt Lake City, Utah, United States
dc.contributor.institutionThe Scatter Works, Inc., Tucson, Arizona, United States
dc.contributor.institutionCollege of Optical Sciences, University of Arizona, Tucson, Arizona, United States
dc.contributor.institutionAlcon Laboratories, Inc., Fort Worth, Texas, United States
refterms.dateFOA2018-06-29T23:51:46Z
html.description.abstractPURPOSE. To evaluate light scatter and stray light in intraocular lenses (IOLs) explanted because of postoperative opacification (13 calcified hydrophilic acrylic, 1 calcified silicone, and 4 polymethylmethacrylate [PMMA] lenses with snowflake degeneration), as well as effect of opacification on other optical quality/performance indicators, in comparison with controls. METHODS. The Complete Angle Scatter Instrument (CASI) scatterometer was used to measure the forward light scattering (FLS) of the IOLs, and the stray light values at various angles were calculated from the measured FLS. Modulation transfer function (MTF) was obtained with an optical bench, and a Badal optometer was used to obtain letter chart images through the lenses. Back light scatter and light transmittance were also measured. RESULTS. Average stray light values (Log (s)) at a scattered angle of 100 were 1.79 +/- 0.37 for hydrophilic acrylic IOLs (controls 0.36 +/- 0.05), 1.53 for the silicone lens (control 0.41), and 1.62 +/- 0.46 for PMMA IOLs (control 0.25). Stray light was significantly higher for explanted opacified lenses (N = 18) in comparison with controls (N = 7; two-tail P < 0.001 at 100). Modulation transfer function and Badal image contrast were drastically reduced in lenses with calcification and snowflake degeneration. CONCLUSIONS. Different studies described the impact of stray light in human vision, with serious hindrance above 1.47 Log (s). Lenses explanted from patients because of clinically significant opacification are associated with a considerable increase in light scatter and stray light, as well as with a decline of other optical quality/performance indicators.


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