AuthorBerman, Benjamin P.
Trouard, Theodore P.
Martin, Diego R.
Altbach, Maria I.
AffiliationUniv Arizona, Program Appl Math
Univ Arizona, Dept Elect & Comp Engn
Univ Arizona, Dept Biomed Engn
Univ Arizona, Dept Med Imaging
MetadataShow full item record
CitationVolumetric MRI of the lungs during forced expiration 2016, 75 (6):2295 Magnetic Resonance in Medicine
JournalMagnetic Resonance in Medicine
Rights© 2015 Wiley Periodicals, Inc.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractPurpose: Lung function is typically characterized by spirometer measurements, which do not offer spatially specific information. Imaging during exhalation provides spatial information but is challenging due to large movement over a short time. The purpose of this work is to provide a solution to lung imaging during forced expiration using accelerated magnetic resonance imaging. The method uses radial golden angle stack-of-stars gradient echo acquisition and compressed sensing reconstruction. Methods: A technique for dynamic three-dimensional imaging of the lungs from highly undersampled data is developed and tested on six subjects. This method takes advantage of image sparsity, both spatially and temporally, including the use of reference frames called bookends. Sparsity, with respect to total variation, and residual from the bookends, enables reconstruction from an extremely limited amount of data. Results: Dynamic three-dimensional images can be captured at sub-150 ms temporal resolution, using only three (or less) acquired radial lines per slice per timepoint. The images have a spatial resolution of 4.6 x 4.6 x 10 mm. Lung volume calculations based on image segmentation are compared to those from simultaneously acquired spirometer measurements. Conclusion: Dynamic lung imaging during forced expiration is made possible by compressed sensing accelerated dynamic three-dimensional radial magnetic resonance imaging. (C) 2015 Wiley Periodicals, Inc.
NoteVersion of record online: 3 July 2015; 12 Months Embargo.
VersionFinal accepted manuscript
SponsorsPhoenix Chapter of the ARCS Foundation
- Golden-angle radial sparse parallel MRI: combination of compressed sensing, parallel imaging, and golden-angle radial sampling for fast and flexible dynamic volumetric MRI.
- Authors: Feng L, Grimm R, Block KT, Chandarana H, Kim S, Xu J, Axel L, Sodickson DK, Otazo R
- Issue date: 2014 Sep
- Three-dimensional pulmonary perfusion MRI with radial ultrashort echo time and spatial-temporal constrained reconstruction.
- Authors: Bauman G, Johnson KM, Bell LC, Velikina JV, Samsonov AA, Nagle SK, Fain SB
- Issue date: 2015 Feb
- Semiautomatic assessment of respiratory motion in dynamic MRI--comparison with simultaneously acquired spirometry.
- Authors: Tetzlaff R, Eichinger M, Schöbinger M, Puderbach M, Meinzer HP, Kauczor HU
- Issue date: 2008 Nov
- Influence of temporal regularization and radial undersampling factor on compressed sensing reconstruction in dynamic contrast enhanced MRI of the breast.
- Authors: Kim SG, Feng L, Grimm R, Freed M, Block KT, Sodickson DK, Moy L, Otazo R
- Issue date: 2016 Jan
- Multistage self-gated lung imaging in small rodents.
- Authors: Tibiletti M, Kjørstad Å, Bianchi A, Schad LR, Stiller D, Rasche V
- Issue date: 2016 Jun