Maintenance and Representation of Mind Wandering during Resting-State fMRI
Author
Chou, Ying-huiSundman, Mark
Whitson, Heather E.
Gaur, Pooja
Chu, Mei-Lan
Weingarten, Carol P.
Madden, David J.
Wang, Lihong
Kirste, Imke
Joliot, Marc
Diaz, Michele T.
Li, Yi-Ju
Song, Allen W.
Chen, Nan-kuei
Affiliation
Univ Arizona, Dept PsycholUniv Arizona, Cognit Sci Program
Univ Arizona, Arizona Ctr Aging
Univ Arizona, Dept Biomed Engn
Univ Arizona, Dept Med Imaging
Issue Date
2017-01-12
Metadata
Show full item recordPublisher
NATURE PUBLISHING GROUPCitation
Maintenance and Representation of Mind Wandering during Resting-State fMRI 2017, 7:40722 Scientific ReportsJournal
Scientific ReportsRights
This work is licensed under a Creative Commons Attribution 4.0 International License.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Major advances in resting-state functional magnetic resonance imaging (fMRI) techniques in the last two decades have provided a tool to better understand the functional organization of the brain both in health and illness. Despite such developments, characterizing regulation and cerebral representation of mind wandering, which occurs unavoidably during resting-state fMRI scans and may induce variability of the acquired data, remains a work in progress. Here, we demonstrate that a decrease or decoupling in functional connectivity involving the caudate nucleus, insula, medial prefrontal cortex and other domain-specific regions was associated with more sustained mind wandering in particular thought domains during resting-state fMRI. Importantly, our findings suggest that temporal and between-subject variations in functional connectivity of above-mentioned regions might be linked with the continuity of mind wandering. Our study not only provides a preliminary framework for characterizing the maintenance and cerebral representation of different types of mind wandering, but also highlights the importance of taking mind wandering into consideration when studying brain organization with resting-state fMRI in the future.ISSN
2045-2322Version
Final published versionSponsors
NIH [R01 NS074045, R01 MH098301, R01AG043438, R01 AG039684]Additional Links
http://www.nature.com/articles/srep40722ae974a485f413a2113503eed53cd6c53
10.1038/srep40722