AffiliationUniversity of Arizona College of Pharmacy
MetadataShow full item record
PublisherMEDICAL LIBRARY ASSOC
CitationEvaluation of resources for analyzing drug interactions 2016, 104 (4):290 Journal of the Medical Library Association : JMLA
Rights© 2016, Authors.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractObjective: The research sought to evaluate seven drug information resources, specifically designed for analyzing drug interactions for scope, completeness, and ease of use, and determine the consistency of content among the seven resources. Methods: A cross-sectional study was conducted where 100 drug-drug and drug-dietary supplement interactions were analyzed using 7 drug information resources: Lexicomp Interactions module, Micromedex Drug Interactions, Clinical Pharmacology Drug Interaction Report, Facts & Comparisons eAnswers, Stockley's Drug Interactions (10th edition), Drug Interactions Analysis and Management (2014), and Drug Interaction Facts (2015). The interaction sample was developed based on published resources and peer input. Two independent reviewers gathered data for each interaction from each of the 7 resources using a common form. Results: Eighty-two drug-drug and 18 drug-dietary supplement interactions were analyzed. Scope scores were higher for Lexicomp Interactions (97.0%), Clinical Pharmacology Drug Interaction Report (97.0%), and Micromedex Drug Interactions (93.0%) compared to all other resources (p<0.05 for each comparison). Overall completeness scores were higher for Micromedex Drug Interactions (median 5, interquartile range [IQR] 4 to 5) compared to all other resources (p<0.01 for each comparison) and were higher for Lexicomp Interactions (median 4, IQR 4 to 5), Facts & Comparisons eAnswers (median 4, IQR 4 to 5), and Drug Interaction Facts (4, IQR 4 to 5) compared to all other resources, except Micromedex (p<0.05 for each comparison). Ease of use, in terms of time to locate information and time to gather information, was similar among resources. Consistency score was higher for Micromedex (69.9%) compared to all other resources (p<0.05 for each comparison). Conclusions: Clinical Pharmacology Drug Interaction Report, Lexicomp Interactions, and Micromedex Drug Interactions scored highest in scope. Micromedex Drug Interactions and Lexicomp Interactions scored highest in completeness. Consistency scores were overall low, but Micromedex Drug Interactions was the highest.
VersionFinal published version
- Evaluation of drug information resources for drug-ethanol and drug-tobacco interactions.
- Authors: Beckett RD, Stump CD, Dyer MA
- Issue date: 2019 Jan
- Evaluation of Point-of-Care Resources for Dietary Supplement Information.
- Authors: Montgomery AE, Beckett RD, Montagano KJ, Kutom S
- Issue date: 2018 Jan-Dec
- Clinical decision support tools: analysis of online drug information databases.
- Authors: Clauson KA, Marsh WA, Polen HH, Seamon MJ, Ortiz BI
- Issue date: 2007 Mar 8
- Clinical decision support tools: performance of personal digital assistant versus online drug information databases.
- Authors: Clauson KA, Polen HH, Marsh WA
- Issue date: 2007 Dec
- Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information.
- Authors: Chang JS, Pham DA, Dang MT, Lu Y, VanOsdol S, Shin J
- Issue date: 2016 Jan