• Login
    View Item 
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UA Campus RepositoryCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournal

    My Account

    LoginRegister

    About

    AboutUA Faculty PublicationsUA DissertationsUA Master's ThesesUA Honors ThesesUA PressUA YearbooksUA CatalogsUA Libraries

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Hurley_GQuad_RNA.pdf
    Size:
    13.66Mb
    Format:
    PDF
    Description:
    Final Accepted Manuscript
    Download
    Author
    Weldon, Carika
    Behm-Ansmant, Isabelle
    Hurley, Laurence H
    Burley, Glenn A
    Branlant, Christiane
    Eperon, Ian C cc
    Dominguez, Cyril cc
    Affiliation
    College of Pharmacy and BIO5 Institute, University of Arizona
    University of Arizona Cancer Center
    Issue Date
    2016-11-07
    
    Metadata
    Show full item record
    Publisher
    NATURE PUBLISHING GROUP
    Citation
    Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA 2016, 13 (1):18 Nature Chemical Biology
    Journal
    Nature Chemical Biology
    Rights
    Copyright © 2016 Nature America, Inc., part of Springer Nature.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences in long functional RNA molecules. We developed a new strategy, footprinting of long 7-deazaguanine-substituted RNAs (FOLDeR), that allows the formation of G4s to be confirmed in long RNAs and under functional conditions.
    Note
    6 month embargo; Published online 07 November 2016
    ISSN
    1552-4450
    1552-4469
    PubMed ID
    27820800
    DOI
    10.1038/nchembio.2228
    Version
    Final accepted manuscript
    Sponsors
    Medical Research Council Career Development Award [G1000526]; Bank of Butterfield Foundation in Bermuda; Lorraine University [UMR 7365]; European Alternative Splicing Network of Excellence (EURASNET, FP6 life sciences, genomics and biotechnology for health) [LSHG-CT-2005-518238]; CNRS
    Additional Links
    http://www.nature.com/doifinder/10.1038/nchembio.2228
    ae974a485f413a2113503eed53cd6c53
    10.1038/nchembio.2228
    Scopus Count
    Collections
    UA Faculty Publications

    entitlement

    Related articles

    • The emerging structural complexity of G-quadruplex RNAs.
    • Authors: Banco MT, Ferré-D'Amaré AR
    • Issue date: 2021 Apr
    • Detecting G4 unwinding.
    • Authors: Juranek S, Paeschke K
    • Issue date: 2022
    • Targeted Detection of G-Quadruplexes in Cellular RNAs.
    • Authors: Kwok CK, Balasubramanian S
    • Issue date: 2015 Jun 1
    • Do we know whether potential G-quadruplexes actually form in long functional RNA molecules?
    • Authors: Weldon C, Eperon IC, Dominguez C
    • Issue date: 2016 Dec 15
    • G-quadruplex DNA: A Longer Story.
    • Authors: Monsen RC, Trent JO, Chaires JB
    • Issue date: 2022 Nov 15
    The University of Arizona Libraries | 1510 E. University Blvd. | Tucson, AZ 85721-0055
    Tel 520-621-6442 | repository@u.library.arizona.edu
    DSpace software copyright © 2002-2017  DuraSpace
    Quick Guide | Contact Us | Send Feedback
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.