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    Identification of Apnea Events Using a Chest‐Worn Physical Activity Monitor

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    Author
    Salazar, Eduardo
    Affiliation
    The University of Arizona College of Medicine - Phoenix
    Issue Date
    2017-05-25
    Keywords
    CPAP
    Sleep Monitor
    BioHarness
    Home Setting
    Phase-Space Transformation
    PSG
    MeSH Subjects
    Sleep Apnea Syndromes
    Sleep Apnea, Obstructive
    Support Vector Machine
    Monitoring, Physiologic
    Sensitivity and Specificity
    Therapeutics
    Quality of Life
    Polysomnography
    Continuous Positive Airway Pressure
    Signal Processing, Computer-Assisted
    Biomechanical Phenomena
    Actigraphy
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    Publisher
    The University of Arizona.
    Description
    A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.
    URI
    http://hdl.handle.net/10150/623620
    Abstract
    Obstructive sleep apnea (OSA) is a condition characterized by upper airway obstruction during sleep causing intermittent hypoxia and nighttime awakening. It is a common condition in the United States that is often undiagnosed. It is a significant risk factor for decreased daytime productivity, quality of life, cardiovascular disease, and death. The current gold standard for diagnosis of OSA is laboratory‐based polysomnography (PSG). While PSG is necessary for the diagnosis and monitoring of OSA, many patients have limited access to PSG due to wait times at PSG laboratories or economic or geographic limitations. Portable sleep monitoring has been studied as a possible solution for patients who do not have access to timely PSG. This study aimed to use the Zephyr BioHarness 3, a chest‐worn physical activity monitor that records movement and physiologic data in real‐time, to detect apnea events in patients with suspected OSA undergoing single‐night laboratory PSG. Twenty patients underwent single‐night laboratory‐based PSG while simultaneously wearing the Zephyr BioHarness 3. The Zephyr BioHarness 3 data was analyzed using three methods. First, apnea events were identified in 10‐second windows of Zephyr data via support vector machine, logistic regression, and neural network (sensitivity = 76.0 ± 0.3%, specificity = 62.7 ± 0.2%, accuracy = 63.7 ± 0.1%). Second, apnea events were identified using the mean, median, and variance of the 10‐second windows (sensitivity = 72.3 ± 0.3%, specificity = 69.4 ± 0.1%), accuracy 69.6 ± 0.1%). Third, apnea events were identified using phase‐space transformation of the Zephyr BioHarness 3 data (sensitivity = 76.9 ± 0.3%, specificity = 77.9 ± 0.1 %, accuracy = 77.9 ± 0.1%). The Zephyr BioHarness shows initial promise as a possible OSA screening tool for patients suspected of OSA but who lack access to timely laboratory‐based PSG.
    Type
    text; Electronic Thesis
    Language
    en_US
    Collections
    College of Medicine - Phoenix, Scholarly Projects

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