Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost
Burgess, Shane C.
AffiliationUniv Arizona, Coll Agr & Life Sci
MetadataShow full item record
PublisherBIOMED CENTRAL LTD
CitationCorrespondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost 2017, 18 (1) Genome Biology
Rights© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
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AbstractThrough RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.
NoteOpen Access Journal
VersionFinal published version
SponsorsERC project BATESON; Israel Academy of Sciences [876/14]; Chief Scientist of the Israeli Ministry of Agriculture [0469/14]