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dc.contributor.advisorMayersohn, Michaelen
dc.contributor.authorNii, Sarah
dc.date.accessioned2017-07-18T16:20:25Z
dc.date.available2017-07-18T16:20:25Z
dc.date.issued2005
dc.identifier.urihttp://hdl.handle.net/10150/624765
dc.descriptionClass of 2005 Abstracten
dc.description.abstractObjectives: To determine whether acyclovir and cephalexin produced in Mexico are equivalent in content and uniformity to products made in the United States. Methods: High-pressure liquid chromatography (HPLC) assays were performed on drug samples of Mexican products and U.S. products using U.S. Pharmacopeia – National Formulary (USP-NF) guidelines.5 Content and content uniformity of the products from the U.S. and Mexico were compared. Results: Acyclovir produced in Mexico had 75.4% content and 78.1% content uniformity compared to the acyclovir produced in the United States. The Mexican manufactured cephalexin had 99.0% content and 99.9% content uniformity compared to the U.S. manufactured cephalexin. Implications: Not all Mexican manufactured drugs are equivalent in content and content uniformity to American manufactured drugs.
dc.language.isoen_USen
dc.publisherThe University of Arizona.en
dc.rightsCopyright © is held by the author.en
dc.subjectAcycloviren
dc.subjectCephalexinen
dc.subjectMexicoen
dc.subjectUnited Statesen
dc.subject.meshAcycloviren
dc.subject.meshCephalexinen
dc.subject.meshMexicoen
dc.subject.meshNorth Americaen
dc.titleComparison of Content and Uniformity of American versus Mexican Manufactured Acyclovir and Cephalexinen_US
dc.typetexten
dc.typeElectronic Reporten
dc.contributor.departmentCollege of Pharmacy, The University of Arizonaen
dc.description.collectioninformationThis item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.en
html.description.abstractObjectives: To determine whether acyclovir and cephalexin produced in Mexico are equivalent in content and uniformity to products made in the United States. Methods: High-pressure liquid chromatography (HPLC) assays were performed on drug samples of Mexican products and U.S. products using U.S. Pharmacopeia – National Formulary (USP-NF) guidelines.5 Content and content uniformity of the products from the U.S. and Mexico were compared. Results: Acyclovir produced in Mexico had 75.4% content and 78.1% content uniformity compared to the acyclovir produced in the United States. The Mexican manufactured cephalexin had 99.0% content and 99.9% content uniformity compared to the U.S. manufactured cephalexin. Implications: Not all Mexican manufactured drugs are equivalent in content and content uniformity to American manufactured drugs.


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