Creating a C-12 Series of Glycolipids for Use as Micelles in Drug Delivery
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PublisherThe University of Arizona.
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AbstractMicelles are critically important molecules with a variety of uses. They have historically been used in the multibillion dollar soap industry. More recently, their efficacy in drug delivery has been demonstrated (1). Normal oxygen-linked glycosides are susceptible to hydrolysis (2). We are seeking to develop a series of carbon-linked glycolipids of varying chain lengths and functional groups in order to observe trends in their micelle properties, including Critical Micelle Concentration (CMC). Presented here are the C-12 Glycoside series.
Degree ProgramHonors College