Comparative Genomics of Aspergillus flavus S and L Morphotypes Yields Insight into Niche Adaption
AdvisorOrbach, Marc J.
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PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
EmbargoRelease after 01-Jan-2018
AbstractThis dissertation consists of three manuscripts for publication: Appendix A presents a genomic comparison of Aspergillus flavus isolates with different morphologies, and Appendices B and C present the identification and systematics of an emerging snake pathogen, Ophidiomyces ophiodiicola. The comparative genomics project of A. flavus tests the hypothesis that isolates with different morphologies within the species are adapted to different niches. Our results reveal differences in genome structure and protein content that are implicated in niche adaptation to the soil and phyllosphere. The systematics project of O. ophiodiicola was initiated to resolve the frequent misidentification of emerging reptilian diseases that is occuring in the literature. One of these emerging pathogens, O. ophiodiicola, was incorrectly described in the genus Chrysosporium due to its resemblance in spore morphology; therefore, the taxonomy of the genus was revised. We hope the review will aid in accurate identification and tracking of emerging reptilian diseases to better understand their epidemiology.
Degree ProgramGraduate College