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    Rattlesnake Envenomations Treated Without Antivenom

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    Author
    Chang, Phoebe
    Affiliation
    The University of Arizona College of Medicine - Phoenix
    Issue Date
    2018-03-28
    Keywords
    Rattlesnake
    Anti-Venoms
    Envenomation
    MeSH Subjects
    Crotalus
    Antivenins
    Snake Bites
    
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    Publisher
    The University of Arizona.
    Description
    A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.
    URI
    http://hdl.handle.net/10150/627152
    Abstract
    The standard treatment for rattlesnake envenomation (RSE) is antivenom. The clinical course of patients treated with antivenom is well described. Prior to 2000, only a whole IgG AV (IgGAV) associated with high rates of hypersensitivity reactions (HSS) was available to treat RSE. Since 2000, Crotalidae Polyvalent Immune Fab (FabAV), which has a better safety profile than IgGAV, has been primarily used. Patients with RSE may not be treated with AV for a variety of reasons including history or perceived risk of HSS, patient refusal, drug shortage, or clinical impression that AV is not indicated. Research Question: What outcomes are associated with moderate to severe RSEs treated without antivenom?
    Type
    text; Electronic Thesis
    Language
    en_US
    Collections
    College of Medicine - Phoenix, Scholarly Projects

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