Show simple item record

dc.contributor.authorGalvin, Katie*
dc.date.accessioned2018-03-30T19:25:01Z
dc.date.available2018-03-30T19:25:01Z
dc.date.issued2018-03-30
dc.identifier.urihttp://hdl.handle.net/10150/627169
dc.descriptionA Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.en
dc.description.abstractBackground: Eosinophilic esophagitis (EoE) is a non-IgE mediated, antigen-driven disease characterized by eosinophilic inflammation with resultant tissue remodeling, fibrosis, and esophageal dysfunction. The current standard of care requires multiple esophageal biopsies. Eosinophil peroxidase (EPX) is an eosinophil-specific granule protein that serves as a surrogate for eosinophil activity. We aim to develop a rapid, minimally invasive clinical screening test for EoE. We hypothesize EPX from buccal swabs will be elevated in samples from EoE patients versus non-EoE controls.
dc.language.isoen_USen
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.subject.meshEosinophilic Esophagitisen
dc.subject.meshBiomarkersen
dc.titleDevelopment of a non-invasive biomarker of eosinophilic esophagitisen_US
dc.typetext; Electronic Thesisen
dc.contributor.departmentThe University of Arizona College of Medicine - Phoenixen
dc.description.collectioninformationThis item is part of the College of Medicine - Phoenix Scholarly Projects 2018 collection. For more information, contact the Phoenix Biomedical Campus Library at pbc-library@email.arizona.edu.en_US
dc.contributor.mentorWright, Benjaminen
refterms.dateFOA2018-09-12T07:09:04Z
html.description.abstractBackground: Eosinophilic esophagitis (EoE) is a non-IgE mediated, antigen-driven disease characterized by eosinophilic inflammation with resultant tissue remodeling, fibrosis, and esophageal dysfunction. The current standard of care requires multiple esophageal biopsies. Eosinophil peroxidase (EPX) is an eosinophil-specific granule protein that serves as a surrogate for eosinophil activity. We aim to develop a rapid, minimally invasive clinical screening test for EoE. We hypothesize EPX from buccal swabs will be elevated in samples from EoE patients versus non-EoE controls.


Files in this item

Thumbnail
Name:
GalvinK_Poster.pdf
Size:
501.4Kb
Format:
PDF
Thumbnail
Name:
GalvinK_thesis.pdf
Size:
451.3Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record