Successful resolution of hyperammonemia following hematopoietic cell transplantation with directed treatment of Ureaplasma parvum infection
AffiliationUniv Arizona, Dept Pediat
Univ Arizona, Ctr Canc
MetadataShow full item record
CitationGraetz R, Meyer R, Shehab K, Katsanis E. Successful resolution of hyperammonemia following hematopoietic cell transplantation with directed treatment of Ureaplasma parvum infection. Transpl Infect Dis. 2018;20:e12839. https://doi.org/10.1111/tid.12839
JournalTRANSPLANT INFECTIOUS DISEASE
Rights© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
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AbstractHyperammonemia following hematopoietic cell transplantation (HCT) has been characterized as idiopathic and is associated with a very high mortality. A causal relationship between Ureaplasma infection and hyperammonemia in immunocompromised lung transplant recipients has recently been described. We document the first case of hyperammonemia following HCT associated with Ureaplasma parvum. The initiation of appropriate antibiotics resulted in rapid resolution of hyperammonemic encephalopathy and eradication of the implicating organism.
Note12 month embargo; published online: 23 January 2018
VersionFinal accepted manuscript