Successful resolution of hyperammonemia following hematopoietic cell transplantation with directed treatment of Ureaplasma parvum infection
AffiliationUniv Arizona, Dept Pediat
Univ Arizona, Ctr Canc
MetadataShow full item record
CitationGraetz R, Meyer R, Shehab K, Katsanis E. Successful resolution of hyperammonemia following hematopoietic cell transplantation with directed treatment of Ureaplasma parvum infection. Transpl Infect Dis. 2018;20:e12839. https://doi.org/10.1111/tid.12839
JournalTRANSPLANT INFECTIOUS DISEASE
Rights© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractHyperammonemia following hematopoietic cell transplantation (HCT) has been characterized as idiopathic and is associated with a very high mortality. A causal relationship between Ureaplasma infection and hyperammonemia in immunocompromised lung transplant recipients has recently been described. We document the first case of hyperammonemia following HCT associated with Ureaplasma parvum. The initiation of appropriate antibiotics resulted in rapid resolution of hyperammonemic encephalopathy and eradication of the implicating organism.
Note12 month embargo; published online: 23 January 2018
VersionFinal accepted manuscript
- Disseminated Ureaplasma infection as a cause of fatal hyperammonemia in humans.
- Authors: Bharat A, Cunningham SA, Scott Budinger GR, Kreisel D, DeWet CJ, Gelman AE, Waites K, Crabb D, Xiao L, Bhorade S, Ambalavanan N, Dilling DF, Lowery EM, Astor T, Hachem R, Krupnick AS, DeCamp MM, Ison MG, Patel R
- Issue date: 2015 Apr 22
- Ureaplasma parvum causes hyperammonemia in a pharmacologically immunocompromised murine model.
- Authors: Wang X, Greenwood-Quaintance KE, Karau MJ, Block DR, Mandrekar JN, Cunningham SA, Mallea JM, Patel R
- Issue date: 2017 Mar
- Ureaplasma urealyticum Causes Hyperammonemia in an Experimental Immunocompromised Murine Model.
- Authors: Wang X, Karau MJ, Greenwood-Quaintance KE, Block DR, Mandrekar JN, Cunningham SA, Patel R
- Issue date: 2016
- Severe hematuria in a hematopoietic cell transplant recipient caused by Ureaplasma urealyticum not by BK virus or adenovirus infection.
- Authors: Choi GJ, Kim SJ, Kang JM, Choi SR, Yoo KH, Kim YJ
- Issue date: 2018 Aug
- Possible missed diagnosis of Ureaplasma spp infection in a case of fatal hyperammonemia after repeat renal transplantation.
- Authors: Beeton ML
- Issue date: 2016 Sep