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dc.contributor.authorMasri, Samer
dc.contributor.authorZhang, Li S.
dc.contributor.authorLuo, Hao
dc.contributor.authorPace, Edward
dc.contributor.authorZhang, Jinsheng
dc.contributor.authorBao, Shaowen
dc.date.accessioned2018-05-30T17:22:29Z
dc.date.available2018-05-30T17:22:29Z
dc.date.issued2018-05-21
dc.identifier.citationMasri, S., Zhang, L. S., Luo, H., Pace, E., Zhang, J., & Bao, S. (2018). Blast Exposure Disrupts the Tonotopic Frequency Map in the Primary Auditory Cortex. Neuroscience, 379, 428-434.en_US
dc.identifier.issn03064522
dc.identifier.pmid29625214
dc.identifier.doi10.1016/j.neuroscience.2018.03.041
dc.identifier.urihttp://hdl.handle.net/10150/627835
dc.description.abstractBlast exposure can cause various auditory disorders including tinnitus, hyperacusis, and other central auditory processing disorders. While this is suggestive of pathologies in the central auditory system, the impact of blast exposure on central auditory processing remains poorly understood. Here we examined the effects of blast shockwaves on acoustic response properties and the tonotopic frequency map in the auditory cortex. We found that multiunits recorded from the auditory cortex exhibited higher acoustic thresholds and broader frequency tuning in blast-exposed animals. Furthermore, the frequency map in the primary auditory cortex was distorted. These changes may contribute to central auditory processing disorders. (C) 2018 IBRO. Published by Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipDepartment of Defense [W81XWH-11-2-0031]en_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0306452218302392en_US
dc.rights© 2018 IBRO. Published by Elsevier Ltd. All rights reserved.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectblasten_US
dc.subjectauditory cortexen_US
dc.subjectfrequency mapen_US
dc.subjectcentral auditory processing disorderen_US
dc.subjectraten_US
dc.titleBlast Exposure Disrupts the Tonotopic Frequency Map in the Primary Auditory Cortexen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Neurosci Grad Programen_US
dc.contributor.departmentUniv Arizona, Dept Physiolen_US
dc.identifier.journalNEUROSCIENCEen_US
dc.description.note12 month embargo; published online: 4 April 2018en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleNeuroscience
dc.source.volume379
dc.source.beginpage428
dc.source.endpage434


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